osudhkosh

Simacor10mg

Rx
Generic:
Simvastatin
Dosage form:
Tablet
Pack size:
Tablet
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৳ 10.07/unit

Pack: ৳ 10.07

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At a glance

Simvastatin is a statin used to lower high cholesterol and reduce the risk of heart disease. It inhibits HMG-CoA reductase, lowering LDL cholesterol and triglycerides while increasing HDL cholesterol.

Indications
  • Primary hypercholesterolemia (type IIa and IIb)
  • Coronary heart disease and elevated plasma cholesterol
  • High cholesterol
  • Prevention of heart attack and stroke
Dosage

Adult Dose (Oral):

  • Hypercholesterolemia: Start 5-10 mg/day (evening); max 40 mg/day
  • High CV risk: Start 40 mg/day; adjust at 4-week intervals; max 80 mg/day
  • Homozygous FH: 40 mg/day (evening) or 80 mg/day in 3 divided doses
  • With dronedarone/verapamil/diltiazem: Do not exceed 10 mg/day
  • With amiodarone/amlodipine/ranolazine: Do not exceed 20 mg/day

Pediatric Dose (Heterozygous FH, 10-17 years):

  • Start 10 mg/day; increase at 4-week intervals; max 40 mg/day
Side effects

Common Side Effects:

  • Headache, fatigue, insomnia
  • Nausea, constipation/diarrhea, flatulence
  • Abdominal cramps, dyspepsia
  • Myalgia, myositis, myopathy
  • Rhabdomyolysis (rare)
  • Hepatitis, pancreatitis (rare)
Precautions & warnings
  • Do not use in active liver disease or unexplained persistent transaminase elevations
  • Do not use in pregnancy or lactation
  • Chinese patients: Do not use 80 mg/day with niacin
  • Do not use with strong CYP3A4 inhibitors
  • Monitor for myopathy symptoms (muscle pain, weakness)
Simvastatin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.