৳ 3.50/unit
Pack: ৳ 35
৳ 3.50/unit
Pack: ৳ 35
At a glance
Trifluoperazine is a prescription medicine used in the treatment of schizophrenia. It alters thoughts and elevates mood, improving the person's ability to think, feel and behave.
Indications
- Anxiety disorder
- Schizophrenia
- Psychotic disorders
- Nausea and vomiting
Pharmacology
Trifluoperazine is one of the phenothiazine class of compounds. Its most notable action is antagonism at dopamine receptors in the CNS. This action in the limbic system and associated areas of cerebral cortex is the basis of its antipsychotic action, whilst in the medullary chemoreceptor trigger zone it appears to be responsible for the antiemetic effect.
Dosage
Adult Dose (Oral):
- Psychoses/Schizophrenia: Outpatient 1-2 mg every 12 hours; Inpatient initial 2-5 mg every 12 hours; maintenance 15-20 mg/day; not to exceed 40 mg/day
- Anxiety: 1-2 mg twice daily; max 6 mg daily; max duration 12 weeks
Child Dose: 6-12 years: 1 mg once or twice daily; not to exceed 15 mg/day; >12 years: 2-5 mg every 12 hours
Side effects
Common Side Effects:
- Orthostatic hypotension
- Sleepiness
- Dry mouth
- Abnormality of voluntary movements
- Weight gain
- Increased prolactin level in blood
- Urinary retention
- Constipation
- Muscle stiffness
- Tremor
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May affect ability to drive
- May cause dizziness, drowsiness or blurred vision
- Rise slowly if you have been sitting or lying down
- Avoid alcohol
- Inform doctor if abnormal movements of face, lips, jaw and tongue occur
- May increase blood sugar and cholesterol; monitor regularly
- Do not stop suddenly
Overdose effects
Symptoms: Extrapyramidal symptoms, hypotension.
Treatment: Gastric lavage, supportive; anticholinergic/antiparkinsonism drug; fluid replacement.
Storage conditions
Store at room temperature between 15-30°C away from light and moisture.