Sleepon1mg
Rx- Generic:
- Eszopiclone
- Company:
- Silva Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Tablet
৳ 2.01/unit
Pack: ৳ 2.01
At a glance
Eszopiclone — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Eszopiclone is a prescription medicine used to treat insomnia. It reduces sleep onset time and frequent awakening at night. This medicine improves sleep maintenance and therefore ensures sound sleep. Eszopiclone should be taken on an empty stomach, preferably before going to bed. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it is habit forming. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include headache, taste changes, dry mouth, rash, anxiety, respiratory tract infections or viral infections. However, these are temporary and resolve on their own after some time. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you and do not take alcohol with it as it may worsen the dizziness. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, hallucinations or suicidal thoughts while taking this medicine. Consult your doctor before taking this medicine if you are suffering from any liver or kidney problems. You should avoid smoking and alcohol while using this medicine. Pregnant and breastfeeding mothers should not use this medicine. However, if the need arises, please consult your doctor before using it. Eszopiclone belongs to a group of medicines called sedative-hypnotics. It works by slowing activity of the nerve cells in the brain and helps fall asleep.
Indications
• Insomnia
Mechanism of action
Eszopiclone is an S-enantiomer of zopiclone; a nonbenzodiazepine hypnotic of the cyclopyrrolone class. It is structurally unrelated to pyrazolopyrimidines, imidazopyridines, benzodiazepines, barbiturates, or other known drugs with similar hypnotic activity. The exact mechanism of action is unknown, its effect is associated with the interaction with gamma-aminobutyric acid (GABA)-receptor complex at binding domains found near to or allosterically coupled to benzodiazepine receptors.
Dosage
Adult Dose: Oral Insomnia Adult: 1 mg immediately before bedtime, may increase to 2 or 3 mg if necessary. Max: 3 mg daily. Elderly: Max: 2 mg daily. Hepatic impairment: Severe: Max: 2 mg daily. Child Dose: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Eszopiclone is to be taken empty stomach.
Side effects
Common: • Sleepiness • Dizziness • Headache • Taste change • Dryness in mouth • Rash • Anxiety • Hallucination • Respiratory tract infection • Viral infection
Precautions & warnings
[UNSAFE] Eszopiclone may cause side effects which could affect your ability to drive. Eszopiclone may impair alertness and motor coordination, including the risk of morning impairment this risk increases with dose and this may affect your ability to drive. Your doctor has prescribed ZOLNITE 2 MG TABLET to help you fall asleep faster and sleep for longer. It is best taken without food as a high-fat meal can reduce its absorption and effect. Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours. It makes you feel dizzy next morning. Don't drive or do anything requiring concentration until you know how it affects you. It does not affect total sleep time. However, it reduces sleep onset time and frequent awakening at night. Never share your medication with any other person who also has a sleep problem. Inform your doctor if your sleep doesn’t improve after 7 to 10 days of treatment. Stop taking medication and inform your doctor If you experience sleep driving or memory loss. Inform your doctor if you notice behavioral changes, new or worsening depression or suicidal thoughts. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Inform your doctor if you have a history of depression, drug/alcohol abuse, and liver disease. Do not stop taking medication suddenly as it may lead to anxiety, mood changes, and restlessness.
Contraindications
Hypersensitivity
Drug interactions
Concurrent use of CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, clarithromycin, nefazodone, troleandomycin, ritonavir, nelfinavir) may decrease metabolism and increase plasma concentrations of Eszopiclone; dosage reduction of Eszopiclone may be needed. Concurrent use with CYP3A4 inducers (e.g. rifampicin) may reduce concentrations of Eszopiclone. May enhance adverse CNS effects when used with alcohol, anticonvulsants, antihistamines, or other psychotropic drugs. Concurrent use with flumazenil may diminish the sedative effect of nonbenzodiazepine hypnotics.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Eszopiclone.
Use in pregnancy
[CONSULT YOUR DOCTOR] Eszopiclone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Eszopiclone is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Baby should be monitored for excessive sleepiness.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Eszopiclone is safe to use in patients with kidney disease. No dose adjustment of Eszopiclone is recommended. [CAUTION] Eszopiclone should be used with caution in patients with severe liver disease. Dose adjustment of Eszopiclone may be needed. Please consult your doctor. Limited information is available on the use of Eszopiclone in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Common questions
I am suffering from insomnia Take zzowin tablet 2 tablet at night Insomnia, lack sleep and calmness Take zzowin tablet 2Tablet at night, brahmi vati 2 tablet twice Insomnia,can I take Rilanx cap from atrimed,as it contains Jatamansi Take Tagar tablet 2 tablet twice Ayurvedic is good for insomnia people.i have insomnia https://www.1mg.com/otc/jiva-sleep-well-tablet-otc329958One ?one capsules morning & evening after taking food , use at least 1-2 months UTI since last 3 years,. Insomnia for last one month Take syp neeri 10 ml twice, chandraprabha vati 2 tablet twice, gokshuradi guggul 2 tab twice with water before meal for 2 monthsFor insomnia do regular head massage tablet tagar 2 tablet twice, do yoga and pranayam I suffer from insomnia for the last 20 years now l take half tablet of ZOLFRESH 5 mg tablet but get. a hangover next day so please suggest some better tablet for which l will be ever grateful Thanks PATIENT Take Zolfresh at the time of going to bed. It is a short acting drug and suitable for Insomnia for you. also follow the sleep hygiene Insomnia not getting proper sleep in night 1 year old problem. Take tagar tablet 2 tablet in night, add Brahm rasayan 1 spoon twice with water How to reduce insomnia which my pt is having since last 8 months https://www.1mg.com/otc/jiva-sleep-well-tablet-otc329957One ?one tablet morning & evening after taking food , use at least 1-2 months