Solina 10
Rx- Generic:
- Solifenacin Succinate
- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (14 Tablet)
৳ 20/unit
Pack: ৳ 280
At a glance
Solifenacin Succinate — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Solifenacin Succinate is a muscarinic antagonist that is used in the treatment of overactive bladder. It relieves urinary symptoms like frequent urination, urgent need to urinate and inability to control urination. Solifenacin Succinate is advised to take it in a dose and duration as per prescription. It can be taken with or without food. Swallow the medicine as a whole without crushing or chewing it. You should not stop taking the medicine without consulting the doctor as it may lead to the worsening of your symptoms. The course of the treatment should be completed for better efficacy of the medicine. Some common side effects of this medicine are dry mouth, constipation, nausea, and urinary tract infection. To avoid or cope up with the side effects, you must drink plenty of water. It may also lead to blurry vision or dizziness, so it is advised to avoid driving while on the medication. Before receiving the treatment, inform your doctor if you are on any medication for any other health condition. If you are pregnant or breastfeeding, tell your doctor prior to the treatment. Patients with liver or kidney disease must be cautious while receiving the prescription, and they must receive regular follow-ups as per the doctor's advice. Solifenacin Succinate is an antimuscarinic. It works by relaxing muscles of the urinary bladder to prevent frequent, urgent or uncontrolled urination.
Indications
• Overactive bladder (OAB) symptoms
Mechanism of action
Solifenacin is a selective M3 antimuscarinic that inhibits muscarinic receptors resulting in decreased urinary bladder contraction, increased residual urine volume and decreased detrusor muscle pressure.
Dosage
Adult Dose: Oral Overactive bladder Adult: 5 mg once daily. If well tolerated, may increase to 10 mg once daily if needed. For patients who are concurrently taking CYP3A4 inhibitors (e.g. ketoconazole, ritonavir): Max dose: 5 mg once daily. Hepatic impairment: Child-pugh class B: Max: 5 mg daily; Child-pugh class C: Use is not recommended. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Max: 5 mg daily.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Solifenacin Succinate may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Solifenacin Succinate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Dryness in mouth • Constipation • Blurred vision • Nausea • Upset stomach • Urinary tract infection
Precautions & warnings
[UNSAFE] Solifenacin Succinate may cause side effects which could affect your ability to drive. Solifenacin Succinate may cause blurred vision and sometimes sleepiness or tiredness which may affect your ability to drive. Solifenacin Succinate helps you to have better control over your urination by relaxing your bladder which increases its capacity to hold urine, thereby reducing the need to pass urine. It may cause blurred vision, fatigue and sleepiness. Be cautious while driving or doing anything that requires focus. It may cause dry mouth. Try chewing on sugar-free gum or taking small sips of water. Avoid caffeine, alcohol or carbonated drinks as they can worsen your symptoms. Do not stop taking this medicine if you do not notice an improvement in your symptoms as it may take some time for your bladder to adapt and your symptoms to improve.
Contraindications
Uncontrolled narrow-angle glaucoma, urinary retention, gastric retention.
Drug interactions
May interfere with the prokinetic effects of cisapride and metoclopramide. Potentially Fatal: May reduce the stimulatory effect of secretin. Concurrent use with biperiden, orphenadrine, procyclidine or trihexyphenidyl may cause anticholinergic effects such as confusion and loss of bladder control; a washout period of 1 wk between using these drugs is recommended. May increase the ulcerogenic effect of potassium chloride. Strong CYP3A4 inhibitors (e.g. ketoconazole, fluconazole, itraconazole, erythromycin, telithromycin, clarithromycin, ritonavir, indinavir, nelfinavir, nefazodone, aprepitant, verapamil) may reduce the metabolism of solifenacin, thus increasing its plasma levels.
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Solifenacin Succinate. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Solifenacin Succinate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Solifenacin Succinate is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Long-term use of Solifenacin Succinate might reduce milk production, and cause constipation, dry mouth and urine infection in the baby.
Renal / hepatic impairment
[CAUTION] Solifenacin Succinate should be used with caution in patients with severe kidney disease. Dose adjustment of Solifenacin Succinate may be needed. Please consult your doctor. Use of Solifenacin Succinate is not recommended in patients undergoing kidney dialysis. [CAUTION] Solifenacin Succinate should be used with caution in patients with liver disease. Dose adjustment of Solifenacin Succinate may be needed. Please consult your doctor. Use of Solifenacin Succinate is not recommended in patients with severe liver disease.
Common questions
i m taking this tablet soliten 5mg i just want to know does it have any affect on pregnancy I don't know the name Frequent urine desire and not able to hold. Doctor has adviced to take one tab of Solitral at bed time. is there any alternative medicine to Solitral which is cheaper Try Soliten, bispec m not sure about cost I feel some time to urine again after urine but no pain fever burning sensation last time I show to one doctor can u check the report is any abnormal This microsopic report is normal U may be having overactive bladder get urodynamics bladder pressure study Sir my daughter PATIENT a uti patient.puss cells are 10-15 .urine culture is normal. Usg shows overactive bladder she is taking dariff And contiflo.how much time will it take for her treatment with this medicine. y is she taking contiflo icon for overactive bladder Urine leakage, overactive bladder Hi kindly share details history & reports Overactive bladder having frequent urination. Cannot control urge of urine. https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thanks Overactive urinary bladder is my problem. But I'd like to change the medication because of side effects from the present drug I'm using. Take mahayograj guggul 2 tab twice, chandraprabha vati 2 tablet twice with water. Do Yoga and pranayam Getting a overactive bladder thing Continuous urination problem really pissing me off Can't able to control that feeling Get urine routine examination n culture done