osudhkosh
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Company•Unimed Unihealth Pharmaceuticals Ltd.

Sotalex 80

Rx
Generic: Sotalol Hydrochloride

৳ 10/unit

Pack: ৳ 100

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At a glance

Sotalol Hydrochloride is a non-cardioselective beta-blocker and Class III antiarrhythmic used for the treatment of serious arrhythmias such as ventricular tachyarrhythmias and supraventricular tachycardia.

Indications
  • Life-threatening ventricular tachyarrhythmias
  • Symptomatic non-sustained ventricular tachyarrhythmias
  • Paroxysmal atrial tachycardia or fibrillation
  • Paroxysmal AV re-entrant tachycardias
  • Maintenance of sinus rhythm after cardioversion
Pharmacology

Sotalol blocks beta-1 receptors in the sinus node to reduce heart rate and slows AV nodal conduction. It prolongs cardiac action potential phase 3 (by blocking potassium channels), increasing refractory periods and preventing re-entry arrhythmias.

Dosage

Adult Dose (Oral):

  • Starting: 80 mg/day (single or 2 divided doses); increase gradually every 2-3 days
  • Usual dose: 160-320 mg/day in 2 divided doses
  • Life-threatening ventricular arrhythmias: Start 80 mg twice daily; increase every 3 days; max 480-640 mg/day
  • Dose adjustment in renal impairment
Side effects

Common Side Effects:

  • Dizziness
  • Fatigue
  • Slow heart rate (bradycardia)
  • Breathlessness
  • Weakness
  • Nausea, vomiting, taste change, diarrhea
Use in pregnancy

Use in Pregnancy: Generally safe; animal studies show low or no adverse effects; limited human data; consult your doctor.

Pregnancy Category: D — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not use in bronchial asthma or history of COPD
  • Do not use in sick sinus syndrome, sinus bradycardia, 2nd/3rd degree AV block
  • Do not use in uncontrolled heart failure, cardiogenic shock, hypotension
  • Do not use in severe renal impairment (CrCl <10)
  • Caution in pregnancy and lactation
Overdose effects

Overdose: Excessive bradycardia, hypotension, congestive heart failure, bronchospasm, hypoglycemia; symptomatic treatment, atropine, glucagon, β-agonists, pacing.

Storage conditions

Store in a cool and dry place, protected from light; keep out of reach of children.

Sotalol Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.