Spotex 50gm Cream0.1%
OTC- Generic:
- Tretinoin
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Cream
- Pack size:
- 50gm tube
৳ 500/unit
Pack: ৳ 500
At a glance
Tretinoin — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Tretinoin is a form of vitamin A that is used to treat acne which appears as spots or pimples on your face, chest or back. It also helps to smooth rough facial skin and to reduce fine wrinkles on the skin. Tretinoin reduces excessive oil production of the skin. Ideally, a pinpoint application at nighttime is recommended for the duration prescribed by your doctor. The amount you need and for how long you need to take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of this medicine. Follow your doctor's instructions. You should not apply it to damaged or broken skin and avoid contact with your mouth, eyes and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. Consult your doctor again if you do not notice any improvement after a few weeks. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase the side effects. The most common side effects include irritation, dryness and redness of the skin. They are usually mild and improve as your body gets used to the medicine. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. Let your doctor know if these side effects bother you or do not go away. Serious side effects with this medicine are rare. This medicine may make you more sensitive to sunlight so you should limit exposure to the sun if possible. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. Pregnant women or women who are planning to get pregnant should not use this medicine as it can lead to birth defects. Tretinoin is a form of vitamin A. When applied on skin, it reduces oil production in the skin, replenishes acne-prone skin and helps keep your pores open.
Indications
• Acne
Mechanism of action
Tretinoin is a trans-retinoic acid form of vitimin A. It stimulates mitosis and turnover of follicular epithelial cells and reduce their cohesiveness. This facilitates extrusion of existing comedones and prevents formation of new comedone. It also exhibits thinning effect on the stratum corneum. In acute promyelocytic leukaemia, it induces cellular differentiation and decreases proliferations.
Dosage
Adult Dose: Oral Acute promyelocytic leukaemia Adult: Remission induction: 45 mg/m2 daily in 2 divided doses. Treatment is continued until 30 days after complete remission or up to 90 days, whichever occurs first. Hepatic impairment: Reduce dose to 25 mg/m2 daily. Child Dose: Oral Acute promyelocytic leukaemia Child: Remission induction: 1-16 yr 45 mg/m2 daily in 2 divided doses. Treatment is continued until 30 days after complete remission or up to 90 days, whichever occurs first. Hepatic impairment: Reduce dose to 25 mg/m2 daily. Renal Dose: Renal impairment: Reduce dose to 25 mg/m2 daily.
Administration
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Missed dose
If you miss a dose of Tretinoin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Erythema (skin redness) • Skin irritation • Dry skin • Dry lips • Pale red skin • Increased sensitivity to light
Precautions & warnings
No interaction found/established You have been prescribed Tretinoin for the treatment of acne. Clean the affected area with water and a non-medicated soap. Let it dry for 20-30 minutes before applying Tretinoin. It may increase the severity of the spots or pimples in the first few weeks of use. Continue using it as prescribed by your doctor. It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists. Avoid exposure to sunlight while using Tretinoin as it increases the sensitivity of your skin. Use protective measures such as sunscreen or protective clothing. Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile. Avoid taking tetracycline (e.g. doxycycline) as it may reduce the Tretinoin activity. Do not use Tretinoin if you are pregnant. Inform your doctor if excessive skin dryness or skin sensitivity take place.
Contraindications
Hypersensitivity to retinoids. Application to eczematous, sunburnt or abraded skin. Pregnancy, lactation.
Drug interactions
Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides. Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.
Food interactions
No interaction found/established
Use in pregnancy
[CONSULT YOUR DOCTOR] Tretinoin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Tretinoin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
No interaction found/established No interaction found/established
Common questions
Cream to completely fade deep hyper pigmentation face *cream to completely fade out deep hyper pigmentation on face near mouth D acne cream homoeo shop Dear sir i want to any cream for removing the acne pimples from the face First acne severity need to be assessed in the clinic. I give tailor made treatment to my Acne patients i use acne uv-spf 30 cream for daily.can i use this cream at night.please suggest any best night cream same as acne uv product Please upload the pictures of affected area for accurate diagnosis and treatment. Can I use ezanic cream 10% w/w for my acne??? Yes u can depending on the condition of the acne Acne & dark spot removal best cream Faceclin gel twice daily over affected area. Apply Photoscreen Depigment cream once weekly at night ( very little on marks only). Rejuglow face wash/Episoft OC cleanser/Saslic DS wash. Tab.Limcee 500mg once daily for one month. Tab.Ascazin twice daily for one month.Combination peels to clear face & spots, done at skin clinic by dermatologist. I have acne on face and acne marks Please prescribe something to stop acne and clear my face from acne marks https://www.1mg.com/otc/jiva-turmeric-cream-otc329911use this cream at least 3-4 months Which gel or cream contains clindamycin and adapalene for acne pls tell the gel or cream which contains these so that i can start my treatment i expect a reply For Acne- Faceclin Gel For application twice daily over affected area. My face on acne & acne scar problem Please provide best treatment cream Orange peel and Fuller's earth for local application, Chirayata plus capsules aarogyavardhini vati and swadishta virechan Churna as oral medication