Starfil 50
Rx- Generic:
- Sildenafil
- Company:
- Benham Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (4 Tablet)
৳ 35/unit
Pack: ৳ 140
At a glance
Sildenafil — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Sildenafil is a prescription medicine used to treat erectile dysfunction (impotence) in men. It works by increasing blood flow to the penis. This helps men to get or maintain an erection. It belongs to a group of medicines known as phosphodiesterase type 5 (PDE 5) inhibitors. Sildenafil may be taken on an empty stomach or with a meal. It should be strictly taken as advised by your doctor. You should take it about 1 hour before you plan to have sex. The amount of time it takes to work varies from person to person, but it normally takes between 30 minutes and 1 hour. This medicine will only help you to get an erection if you are sexually stimulated. However, you should not take this medicine if you do not have erectile dysfunction. It should not be taken more than once a day. The most common side effects of this medicine are flushing (sense of warmth), headache, dizziness, blurred vision, muscle pain, stomach upset, and rash. Talk to your doctor if any of the side effects bother you or do not go away. This medicine is not intended for use by women and men should avoid using any other medicines to treat impotence without talking to a doctor first. It can be dangerous to take it along with medicines called nitrates (often given for chest pain or angina). Do not take this medicine if you have severe heart or liver problems, have recently had a stroke or heart attack or if you have low blood pressure. Let your doctor know if you suffer from these or any other health problems before taking it. You should not drive if this medicine makes you feel dizzy. Avoid drinking alcohol while taking this medicine as it increases the chances of side effects. Sildenafil is a phosphodiesterase-5 (PDE-5) inhibitor. It works by relaxing the blood vessels in your penis, thereby increasing blood flow into the penis on sexual stimulation. This helps you achieve and maintain a hard, erect penis suitable for sexual activity.
Indications
• Erectile dysfunction
Mechanism of action
Sildenafil inhibits phosphodiesterase type-5 (PDE5) which is responsible for cGMP degradation in the corpus cavernosum. Inhibition of PDE5 increases cGMP levels in the corpus cavernosum which results in smooth muscle relaxation and inflow of blood to the corpus cavernosum.
Dosage
Adult Dose: Oral Erectile dysfunction Adult: 50 mg about 1 hr before sexual intercourse. May adjust dose depending on penile response. Max: 100 mg/dose and not to be taken > once in 24 hr. Elderly: >65 yr: Lower initial dose at 25 mg. Hepatic impairment: Initially, 25 mg. Pulmonary Arterial Hypertension 20 mg 3 times daily, administered 4-6 hours apart Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Initially, 25 mg.
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sildenafil may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Sildenafil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Flushing (sense of warmth in the face, ears, neck and trunk) • Headache • Blurred vision • Muscle pain • Upset stomach • Altered vision • Rash
Precautions & warnings
[UNSAFE] Sildenafil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Sildenafil for the treatment of erectile dysfunction. It is best to take it an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity. Do not take it more than once a day. Seek medical attention if the erection persists for more than 4 hours after sexual intercourse. Do not use Sildenafil if you have recently taken nitrates (medicines used in angina or chest pain). Do not take it if you have had a heart attack in the past 3 months, or stroke or heart failure in the past 6 months.
Contraindications
Hypersensitivity. Patients concurrently or intermittently using organic nitrates in any form.
Drug interactions
Inhibitors of CYP3A4 such as cimetidine and erythromycin are likely to reduce sildenafil clearance. CYP3A4 inducers such as rifampicin may decrease the plasma concentrations of sildenafil. Symptomatic hypotension when used with beta-blockers. Plasma concentrations are increased by ritonavir. Potentially Fatal: May potentiate hypotensive effects of of organic nitrates and nicorandil.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Sildenafil.
Use in pregnancy
[CONSULT YOUR DOCTOR] Information regarding the use of Sildenafil during pregnancy is not available. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Sildenafil during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Sildenafil is safe to use in patients with kidney disease. No dose adjustment of Sildenafil is recommended. However, inform your doctor if you have any underlying kidney disease. A lowering of dose may be considered if it is not well-tolerated. [CAUTION] Sildenafil should be used with caution in patients with severe liver disease. Dose adjustment of Sildenafil may be needed. Please consult your doctor. There is limited information available on the use of Sildenafil in patients with severe liver disease.
Common questions
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