Streptase15LacIU
Rx- Generic:
- Streptokinase
- Company:
- Rainbow Traders
- Dosage form:
- Injection
- Pack size:
- Injection
৳ 3,757.01/unit
Pack: ৳ 3,757.01
At a glance
Streptokinase — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Streptokinase is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke. Streptokinase is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition till you became stable. Use of this medicine may cause injection site bleeding, allergic reaction, and decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly. Streptokinase works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
Indications
• Heart attack • Pulmonary embolism
Mechanism of action
Streptokinase forms a complex with plasminogen which then converts plasminogen to plasmin. Plasmin breaks down clots as well as fibrinogen and other plasma proteins.
Dosage
Adult Dose: Intravenous Acute myocardial infarction Adult: 1.5 million units as a single dose infused over 1 hr immediately after onset of symptoms. Pulmonary thromboembolism ; Arteriovenous occlusions Adult: Loading dose: 250,000 units infused over 30 min. Maintenance: 100,000 units/hr for 24-72 hr depending on the condition to be treated. For cerebral retinal thrombosis, 12 hr may be sufficient. Monitor treatment by maintaining thrombin clotting time at 2-4 times normal values. Child Dose: Intravenous Pulmonary thromboembolism ; Arteriovenous occlusions Child: Loading dose: 2500-4000 units/kg over 30 min, followed by infusion of 500-1000 units/kg/hr, continued until reperfusion occurs, up to 3 days. Initial dose may be estimated by streptokinase resistance test. Monitor treatment by maintaining thrombin clotting time at 2-4 times normal values.
Administration
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Missed dose
If you miss a dose of Streptokinase, please consult your doctor.
Side effects
Common: • Allergic reaction • Nausea • Vomiting • Injection site bleeding
Precautions & warnings
[NOT RELEVANT] Not relevant, as Streptokinase is intended for use in hospitalised patients. It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling). Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Contraindications
Severe hypertension, recent stroke, cerebral neoplasm, recent history of peptic ulcer disease, ulcerative colitis, pancreatitis, subacute bacterial endocarditis, coagulation defects also due to liver or kidney disease, recent surgery, childbirth. Hypersensitivity, increased risk of cerebral bleeding, trauma. Pregnancy. Active internal bleeding, bleeding GI lesions. Arteriovenous malformation or aneurysm; recent (within 10 days) facial or head trauma, intracranial or intraspinal surgery, More than 5 days and less than 12 months since previous Streptokinase therapy.
Drug interactions
Antagonistic effects with antifibrinolytic agents e.g. aminocaproic acid. Potentially Fatal: Anticoagulants, heparin, antiplatelet agents e.g. aspirin and dipyridamole affect platelet function increasing the risk of haemorrhage.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Streptokinase. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Streptokinase may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Information regarding the use of Streptokinase during breastfeeding is not available. Please consult your doctor.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Streptokinase is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Streptokinase may not be needed in these patients. Please consult your doctor. Use of Streptokinase is not recommended in patients with severe kidney disease. [CAUTION] Streptokinase should be used with caution in patients with severe liver disease. Dose adjustment of Streptokinase may be needed. Please consult your doctor.
Common questions
In road accident head and small intestine got injured . 15 stiches on head and operation of 1 inch diameter of intestine . Now spo2 level is dropping to 70% after 1 hour of removing oxygen mask Get checked for pulmonary embolism or pneumothorax GE my self v.k tiwari mbbs md i feel the patient information above is there any blood test for diagnosed pulmonary edema and pulmonary embolism Dear Sir There is no specific blood test for diagnosing pulmonary edema and embolism I am suffering from pulmonary embolism. I want to know will i die because of this disease ? What is d extent of your disease My Lungs operation on 2012 april.Trobo Entartectome The Right and left preliminary have Trombus Doctor Remove the trobus.Left side is more.PTINR level For 10 Days 2.2 TO 2.6 Now the days left chest side and Right side is always pain.Ecg checked. Bp.110/80.pulse 76.all relevent medical bloodl test ok.Pl Advice me return email I look have to receive your reply.Thank you.Jwala.m.m.If need I will forward you my all test reports Tab.Asitrom.5.5mg.Atorbrst.20.Fruselac Ds Tab.Caverta Sildinafil Tab.8mg 3 times Every Day.Digoxin.0.25mg. dear Mr Jwala. Your condition is coomplex. Pain after pulmonary embolism may be due to lung infarcts. please discuss with treating cardiologist and pulmonologist Hrert attack home made best treatment Well there is no home remedy for heart attackBut Post - Attack to strengthen the heart you can give Arjuna Ksheerapak Respected sir/Madam , please make me sure that if my potassium and other electrolytes are normal, then why I'm feeling symptoms like hypokalemia (leg muscle cramps, confusion and heart palpitations,chest pain, fatigue, illness etc. Is this Pulmonary embolism? Dear PATIENT from 1mg. The reports which you have shared are normal, Please consult a Physician if you have those symptoms. What is heart attack? When heart attack coming? Related to chest pain angina commonly What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection Heart attack, Kidney problems all u can get