Supotaria 0.2

• Pre-operative antimuscarinic agent: to reduce salivary, tracheobronchial and pharyngeal secretions and to reduce gastric acidity
• Intra-operative antimuscarinic: to attenuate or prevent bradycardia due to suxamethonium or cardiac vagal reflexes
• Reversal of neuromuscular blockade: to protect against peripheral muscarinic actions of neostigmine and pyridostigmine
• Peptic Ulcer: adjunctive therapy in adults

Pre-anesthetic (Adults):

• 0.2-0.4 mg IV or IM before induction of anesthesia
• or 0.004-0.005 mg/kg (max 0.4 mg)

Pre-anesthetic (Children 1 month-12 years):

• 0.004-0.008 mg/kg (max 0.2 mg) IV or IM

Intraoperative (Adults):

• 0.2-0.4 mg (or 0.004-0.005 mg/kg, max 0.4 mg) IV

Reversal of Neuromuscular Blockade:

• Adults: 0.2 mg IV per 1 mg neostigmine
• Children: 0.01 mg/kg IV with 0.05 mg/kg neostigmine

* Use as directed by the registered physician

Common Side Effects:

• Dry mouth
• Constipation
• Tachycardia
• Palpitations
• Urinary retention
• Blurred vision
• Photophobia
• Flushing
• Nausea
• Dizziness

Precautions:

• Use with caution in Down's syndrome, children and elderly
• Caution in gastro-esophageal reflux disease, diarrhea, ulcerative colitis
• Caution in acute myocardial infarction, hypertension, hyperthyroidism
• Avoid repeated or large doses in uremia patients
• Caution in myasthenia gravis