Syncapone 10025mg+200mg+100mg

Carbidopa + Entacapone + Levodopa is a prescription medicine used in the treatment of Parkinson's disease. This medicine helps to reduce excessive shaking by slowing down the body movements. It works by increasing the amount of chemical messenger that is needed to control abnormal movements. Carbidopa + Entacapone + Levodopa is taken with or without food, but better to avoid high protein meal and dairy products. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor and if you have missed a dose, take it as soon as you remember. You should never skip any doses and try to finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it can result in harmful effects. This medicine may cause side effects like nausea, vomiting, constipation, discoloration of urine, and dryness in the mouth. It causes a sudden onset of dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss. Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Carbidopa + Entacapone + Levodopa is a combination of three medicines: Levodopa, Carbidopa and Entacapone which treat Parkinsonism. Levodopa is a Carbidopa precursor which gets converted to dopamine, a chemical messenger that controls movement in the brain. Carbidopa is a peripheral decarboxylase inhibitor which prevents the breakdown of Levodopa allowing it to enter the brain and increase dopamine levels. Entacapone is COMT inhibitor which causes higher and more sustained levels of levodopa in blood, leading to greater relief from the symptoms of Parkinson’s disease.

• Parkinson's disease

Levodopa is the metabolic precurosor of dopamine, it crosses the blood-brain barrier and is converted to dopamine in the brain. Carbidopa increases the amount of levodopa that is transported into the CNS by inhibiting the decarboxylation of peripheral levodopa. Entacapone is a selective inhibitor of catechol-o-methyltransferase. Given concurrently, entacapone results in greater and more substained plasma levels of levodopa, leading to greater control of parkinsonism symptoms.

Adult Dose: Parkinson's disease Adult: PO: Each tab contains levodopa and carbidopa in a ratio of 4:1 and entacapone 200 mg: Initial: 1 tab/day. Titrate dose according to patient's response. Recommended to take only 1 tab per dose administration. Max: 8 tabs/day. Hepatic impairment: Severe: Contraindicated. Child Dose: Safety & efficacy not established

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Carbidopa + Entacapone + Levodopa may be taken with or without food, but it is better to take it at a fixed time. Avoid Carbidopa + Entacapone + Levodopa with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

Common: • Nausea • Vomiting • Constipation • Urine discoloration • Headache • Dryness in mouth • Insomnia (difficulty in sleeping) • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Anxiety • Dizziness • Abnormality of voluntary movements • Abnormal dreams

[UNSAFE] Carbidopa + Entacapone + Levodopa may cause side effects which could affect your ability to drive. Caution is advised when driving or operating machinery. You have been prescribed Carbidopa + Entacapone + Levodopa to treat your symptoms of parkinson's disease. Avoid a high-protein diet (eg.meat, poultry, and dairy products) while you are taking this medicine as that can reduce the amount of medication absorbed by your body. It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Do not stop taking the medication suddenly without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating and confusion. Talk to your doctor in case you develop hallucinations or notice other changes in your behavior.

Hypersensitivity. Narrow angle glaucoma. Should not be used in patients with suspicious, undiagnosed skin lesions or a history ot melanoma.

Increased risk of postural hypotension when used concurrently with hypotensive drugs. Severe orthostatic hypotension may result from concurrent usage with MAOIs. Dopamine D2 receptor antagonists, phenytoin or papaverine may reduce the efficacy of levodopa. Iron salts may reduce the bioavailability. Concurrent usage with drugs that interfere with biliary excretion may lead to increased plasma levels of entacapone. May depress prolactin secretion and increase growth hormone levels.

[UNSAFE] It is unsafe to consume alcohol with Carbidopa + Entacapone + Levodopa.

[CONSULT YOUR DOCTOR] Carbidopa + Entacapone + Levodopa may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Carbidopa + Entacapone + Levodopa is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Carbidopa + Entacapone + Levodopa is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Carbidopa + Entacapone + Levodopa may not be needed in these patients. Please consult your doctor. [CAUTION] Carbidopa + Entacapone + Levodopa should be used with caution in patients with liver disease. Dose adjustment of Carbidopa + Entacapone + Levodopa may be needed. Please consult your doctor.

Parkinson's disease tremors ,Insomnia. Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months My mother suffering from Parkinson disease from 7 year , any affective medicine ?? Both hand and leg is shaking ,hardly stand up from bed himself, using parking tablet, syndopa plus and parkitidin Dear sir Parkinson's can only be managed with Homeopathy. There are few medicines which are used to improve quality of life and decrease disease progression Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result . Hi my mom had Parkinson's disease but didn't get any operation but using tablets syndopa last night she take another tablet of pain killer with it by the morning my mom to full shivering of hands and legs so what do u suggest to do? need to examine to opine My father suffering from Parkinson's disease Suffering from last 7year Treatment is going on of neurologist yes than what is the problem treatment for Parkinson's disease taking now syndopa cr 125, raslect n other medicine isn't this disease fully curable pls help n give u r opinion MEDICINE CONTROLS THE SYMTOMS. IF MEDICINES FAIL TO CONTROL THE DEEP BRAIN STIMULATION SURGERY IS BEING DONE. At times my fingers shiver when I hold cup, paper etc it's subconscious as in I do not notice it person Accompanying me notices I have no other health issues. Does this indicate Parkinson's disease? How is it diagnosed? not sure; show to neuro My father has parkinson's disease from last 12 year. In last 2012 he got severe pneumonia and has been admitted in AIIMS .He was treated with various antibiotics.he came out but got bed ridden after that.From last few year he just sit on his own. he is currently taking bexol 1mg three times, syndopa 125 plus 3 times, ropark XL 3 times.now from few year he got hallucination and cound not sleep in night and constantly talking in night(Some Nights not always).During his stay in AIIMS Dr. prescribed quetiapine 12.5 mg which he is not currently taking.please advice some medicien so that he atleast can sleep at night. Start Oleanz 2.5 mg at nite