osudhkosh

Tacrocap 0.5

Rx
Generic:
Tacrolimus
Dosage form:
Capsule
Pack size:
Strip (10 Capsule)
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৳ 28/unit

Pack: ৳ 280

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At a glance

Tacrolimus is a calcineurin-inhibitor immunosuppressant used for the prophylaxis of organ rejection in allogeneic liver, kidney, heart, and lung transplants.

Indications
  • Prophylaxis of organ rejection in allogeneic liver transplants
  • Prophylaxis of organ rejection in allogeneic kidney transplants
  • Prophylaxis of organ rejection in allogeneic heart transplants
  • Prophylaxis of organ rejection in allogeneic lung transplants
Dosage

Adult Dose (Oral):

  • Kidney (with azathioprine): 0.2 mg/kg/day; target trough 7-20 ng/mL (months 1-3)
  • Kidney (with MMF/IL-2 antagonist): 0.1 mg/kg/day; target 4-11 ng/mL
  • Liver: 0.10-0.15 mg/kg/day; target 5-20 ng/mL
  • Heart: 0.075 mg/kg/day; target 10-20 ng/mL (months 1-3)
  • Lung: 0.075 mg/kg/day; target 10-15 ng/mL (months 1-3)

Pediatric Dose (Oral):

  • Kidney: 0.3 mg/kg/day; target 5-20 ng/mL
  • Liver: 0.15-0.2 mg/kg/day; target 5-20 ng/mL
  • Heart/Lung: 0.3 mg/kg/day; target 5-20 ng/mL
Side effects

Common Side Effects (≥15%):

  • Abnormal renal function, hypertension
  • Diabetes mellitus, fever, CMV infection
  • Tremor, hyperglycemia, leukopenia
  • Anemia, infection, bronchitis
  • Constipation, diarrhea, headache
  • Abdominal pain, insomnia, paresthesia
  • Peripheral edema, nausea, hyperkalemia
Precautions & warnings
  • New-onset diabetes: Monitor blood glucose
  • Nephrotoxicity: Reduce dose; caution with other nephrotoxic drugs
  • Neurotoxicity (risk of PRES): Monitor neurologic abnormalities; reduce/discontinue
  • Hyperkalemia: Monitor serum potassium
  • Not recommended with sirolimus (liver/heart)
  • Avoid live vaccines
Tacrolimus — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.