Tapazol 5
Rx- Generic:
- Methimazole
- Company:
- Renata Limited
- Dosage form:
- Tablet
- Pack size:
- Strip (30 Tablet)
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৳ 6/unit
Pack: ৳ 180
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At a glance
Methimazole is an anti-thyroid drug used for the treatment of hyperthyroidism. It works by inhibiting the synthesis of thyroid hormones.
Indications
- Graves' disease or toxic multinodular goiter - when surgery or radioactive iodine therapy is not appropriate
- To ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy
Dosage
Adult Dose (Oral):
- Mild hyperthyroidism: 15 mg/day (in 3 divided doses, 8-hour intervals)
- Moderate-severe: 30-40 mg/day
- Severe: 60 mg/day
- Maintenance: 5-15 mg/day
Pediatric Dose: 0.4 mg/kg/day (in 3 divided doses); Maintenance: approximately half of initial dose
Side effects
Common Side Effects:
- Skin rash, urticaria
- Nausea, vomiting, epigastric distress
- Arthralgia, paresthesia
- Loss of taste, hair loss
- Myalgia, headache
- Pruritus, drowsiness, neuritis
- Edema, vertigo, skin pigmentation
- Jaundice, sialadenopathy, lymphadenopathy
Precautions & warnings
- Report immediately if symptoms of agranulocytosis (fever, sore throat) occur
- Discontinue if liver toxicity (transaminases >3x ULN) occurs
- Monitor TSH and free T4 regularly for hypothyroidism
- Avoid use in first trimester of pregnancy (risk of fetal harm)
- Caution during lactation
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.