৳ 750/unit
Pack: ৳ 750
৳ 750/unit
Pack: ৳ 750
At a glance
Tetanus Antitoxin (Equine) BP is used for passive immunization against tetanus, for post-exposure prophylaxis in traumatic wounds and therapeutic treatment of tetanus.
Indications
- Tetanus prophylaxis after injury (non-immune or partially immune individuals)
- Therapeutic treatment of tetanus
Pharmacology
Tetanus Antitoxin (Equine) contains antibodies produced in horses against tetanus toxoid. It neutralizes tetanus toxin, providing immediate passive immunity. Being animal-derived, it carries a risk of allergic reactions.
Dosage
Adult Dose (SC/IM):
- Prophylaxis (general wounds): 3,000-5,000 IU
- Prophylaxis (after 24 hours): 3,000 IU
- Prophylaxis (crush or contaminated wounds): 10,000-20,000 IU
- Under 30 kg: 1,500 IU
- Tetanus treatment: 50,000-100,000 IU (partially IV, remainder IM)
Pediatric Dose (SC/IM):
- Under 30 kg: 1,500 IU
Side effects
Common Side Effects:
- Injection site reactions (pain, tenderness)
- Fever, vomiting, diarrhea
- Bronchospasm, urticaria
Serious (Rare):
- Anaphylactic shock (hypotension, dyspnea)
- Serum sickness (7-10 days after)
- Nephritis, myocarditis, neuritis, polyarthritis
Use in pregnancy
Use in Pregnancy: Adequate information not available; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Extreme caution in allergic diseases (asthma, eczema) or history of allergy to previous antiserum injections
- If no previous serum injection or allergy history, IM may be given
- Give trial dose first in allergic patients
- Observe for at least 30 minutes after injection
Overdose effects
Overdose increases allergic reaction risk; for anaphylaxis, use adrenaline, antihistamines, corticosteroids; provide symptomatic treatment.
Storage conditions
Store at 2-8°C in a refrigerator; do not freeze; protect from light; keep out of reach of children.