Thrombocid15mg/gm
OTC- Generic:
- Pentosan Polysulfate Sodium
- Company:
- ZAS Corporation
- Dosage form:
- Gel
- Pack size:
- 40 gm tube
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৳ 495/unit
Pack: ৳ 495
At a glance
Pentosan Polysulfate Sodium is used for the relief of bladder pain or discomfort associated with interstitial cystitis. It is a polymer of xylose hydrogen sulfate that binds Fibroblast growth factors (FGFs) and other heparin-binding growth factors.
Indications
- Bladder pain or discomfort associated with interstitial cystitis
Dosage
Adult Dose (Oral):
- Recommended dose: 300 mg/day (100 mg capsule three times daily)
- Take with water at least 1 hour before or 2 hours after meals
- Reassess after 3 months; may continue for another 3 months if no improvement
- Clinical value of continued treatment beyond 6 months in non-responders is unknown
Pediatric Dose: Safety and efficacy not established in children under 16 years.
Side effects
Side Effects:
- Rectal hemorrhage (6.3% of patients at 300 mg/day)
- Ecchymosis
- Epistaxis
- Gum hemorrhage
- Alopecia (97% alopecia areata; begins within first 4 weeks of treatment)
- Elevated liver enzymes (at higher doses)
Precautions & warnings
- Weak anticoagulant (1/15 activity of heparin)
- Evaluate patients undergoing invasive procedures or with underlying coagulopathy or increased bleeding risk
- Caution in patients with aneurysms, thrombocytopenia, hemophilia, GI ulcerations, polyps, or diverticula
- Caution in history of heparin-induced thrombocytopenia
- Similar product given subcutaneously/sublingually/IM is associated with delayed immunoallergic thrombocytopenia
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.