Ticaflow 60

Ticagrelor belongs to a group of medicines called antiplatelets or blood thinners. It reduces the formation of harmful blood clots in blood vessels. This helps to prevent a heart attack or stroke in people with heart disease. Ticagrelor is also used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina), who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents in such people. Your doctor will also prescribe aspirin, another antiplatelet medicine, along with it. This medicine may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking this medicine even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke. The most common side effect seen with this medicine is bleeding. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. Some people may develop mild breathlessness after taking this medicine, however, this usually resolves on its own with continued treatment. Let your doctor know if bleeding persists or if the breathlessness worsens or does not go away. Ticagrelor is not suitable for some people. Do not take it if you are bleeding from anywhere in the body such as a stomach ulcer or bleeding within the brain, or if you have severe liver problems. Ticagrelor is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

• Prevention of heart attack and stroke • Heart attack

Ticagrelor and its major metabolite reversibly interact with the platelet P2Y12 ADP-receptor to prevent signal transduction and platelet activation. Ticagrelor and its active metabolite are approximately equipotent.

Adult Dose: Oral Acute coronary syndrome Adult: Loading dose (following ACS event): 180 mg PO (two 90 mg tablets) Maintenance dose (for first year following ACS event): 90 mg PO BID Maintenance dose (after 1 year with history of MI): 60 mg PO BID Administer with aspirin: Initial aspirin loading dose of 325 mg, then maintenance dose of aspirin of 75-100 mg/day; DO NOT exceed aspirin dose of 100 mg/day. Hepatic Impairment Moderate to severe: Contraindicated. Renal Dose: Renal impairment No dosage adjustment needed

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ticagrelor may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Ticagrelor, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Bleeding • Breathlessness

[SAFE] Ticagrelor does not usually affect your ability to drive. For best results, take it at the same time every day. Ticagrelor increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails. Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke. If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Ticagrelor temporarily. You may experience shortness of breath in the initial weeks of therapy. Notify your doctor if it becomes worse or persists for long.

History of Intracranial Hemorrhage: Ticagrelor is not recommended in patients with a history of intracranial hemorrhage (ICH) due to a high risk of recurrent ICH in this population. Active Bleeding: Patients with active pathological bleeding eg, peptic ulcer or intracranial hemorrhage. Severe Hepatic Impairment: Patients with severe hepatic impairment because of a probable increase in exposure, and it has not been studied in these patients. Severe hepatic impairment increases the risk of bleeding because of reduced synthesis of coagulation proteins. Hypersensitivity (eg, angioedema) to ticagrelor or to any of the components.

Aminocaproic acid or tranexamic acid &/or recombinant clotting factor VIIa may augment haemostatis. NSAIDs, oral anticoagulants &/or fibrinolytics, ketoconazole, clarithromycin, nefazodone, ritonavir, atazanavir, rifampin, dexamethasone, phenytoin, carbamazepine, phenobarb, simvastatin >40 mg, digoxin. Increased Cmax & AUC w/ cyclosporine.

[CAUTION] Caution is advised when consuming alcohol with Ticagrelor. Please consult your doctor.

[CONSULT YOUR DOCTOR] Ticagrelor may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Ticagrelor during breastfeeding is not available. Please consult your doctor.

[SAFE IF PRESCRIBED] Ticagrelor is safe to use in patients with kidney disease. No dose adjustment of Ticagrelor is recommended. Limited information is available on the use of Ticagrelor in renal dialysis patients. [CAUTION] Ticagrelor should be used with caution in patients with liver disease. Dose adjustment of Ticagrelor may be needed. Please consult your doctor. Use of Ticagrelor is not recommended in patients with severe liver disease.

Fast symbol of heart attack and stroke risk factors undue fatigue chest pain etc Clotting in right leg.after trying tablet wefron2mg . Xerlton15mg is going on.but itching comes on full body. Itching not stopping.what may be reason for itching. Thodi sans bhi fulti he there ke kidney failure can be reason or heart attackconsult cardiologist and nephrologist Hrert attack home made best treatment Well there is no home remedy for heart attackBut Post - Attack to strengthen the heart you can give Arjuna Ksheerapak What is heart attack? When heart attack coming? Related to chest pain angina commonly What are the trip t normal and high values What should be thresholds for ' no heart'' attack', minor attack and heart attack Hello sir. Thank you for consulting with us. Trop T is read as either positive or increased or not positive. Positive Trop T level indicates heart attack and negative Trop t usually indicates no heart attack. Even in minor heart attack, Trop T is positive. What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection Heart attack, Kidney problems all u can get Medicine is very costly ,please prescribe another low cost generic medicine other substitute is axcer i have indergone angeogram with a stunt.now am using axcer 90mg for bp olimisar M 25 and afternoom ecosprin 75mg and night rozovel f 10mg still how much period i have to use axcer tablets At least 3 to 6 months depending upon reports