Topican2.5%+2.5%

• Local analgesia - on normal intact skin (IV cannulation, venipuncture)
• Surface anesthesia on genital mucous membranes - before minor surgery
• Pretreatment for infiltration anesthesia

Adult Dose (Topical):

• Minor dermal procedures (IV cannulation, venipuncture): 2.5 g/20-25 cm², at least 1 hour
• Major dermal procedures (e.g., skin graft): 2 g/10 cm², at least 2 hours
• Male genital skin (pretreatment): Thick layer, 15 minutes
• Female genital mucous membranes: 5-10 g, 5-10 minutes

Pediatric Dose:

• 0-3 months or <5 kg: Max 1 g, Time 1 hour
• 3-12 months and >5 kg: Max 2 g, Time 4 hours
• 1-6 years and >10 kg: Max 10 g, Time 4 hours
• 7-12 years and >20 kg: Max 20 g, Time 4 hours

Common Side Effects:

• Application site reactions (burning, irritation, itching, redness)
• Skin rash
• Nervousness, dizziness, blurred vision, tremors
• Rare: convulsions, unconsciousness, respiratory arrest, hypotension, bradycardia

• Neonates with gestational age <37 weeks - do not use
• Infants <12 months receiving methaemoglobin-inducing agents - do not use
• Do not apply to mucous membranes, broken or inflamed skin
• Caution in epilepsy, impaired cardiac condition, bradycardia, impaired hepatic function, and severe shock
• Oropharyngeal use may interfere with swallowing and increase aspiration risk (especially in children)