Topiclo NN0.05%+0.50%+100000IU

• Psoriasis (excluding widespread plaque psoriasis, where secondary bacterial or fungal infection is present, suspected or likely to occur)
• Eczema (short courses treatment of recalcitrant eczemas)
• Neurodermatoses
• Other inflammatory conditions which do not respond satisfactorily to less active steroids

Adult Dose (Topical): Apply a thin layer onto the affected area(s) 1-2 times daily until improvement occurs. Not to be used for >7 days without medical supervision. If a longer course is necessary, treatment should not be continued for more than 4 weeks without the patient's condition being reviewed.

Pediatric Dose (>2 years): Same as adult dose. Not recommended for neonates and infants (younger than 2 years).

Common Side Effects:

• Perioral dermatitis
• Striae (especially in flexures)
• Dermal and epidermal atrophy (especially on the face)
• Steroid purpura
• Pigmentation changes
• Hypertrichosis

Serious Side Effects (long-term/large area use): Hypercortisolism (adrenal suppression), Cushing's syndrome, diabetes, hypertension.

• Long-term continuous topical therapy should be avoided where possible, particularly in infants and children (adrenal suppression can occur readily even without occlusion).
• If used in childhood, or on the face, courses should be limited to 5 days and occlusion should not be used.
• If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye (glaucoma might result).
• If used in psoriasis, careful patient supervision is important.
• Flammable; do not use or dry the hair near a fire or flame.
• Not recommended during pregnancy and lactation.