Triovix
150mg+200mg+300mgRx৳ 70/unit
Pack: ৳ 700
৳ 70/unit
Pack: ৳ 700
At a glance
Lamivudine + Nevirapine + Zidovudine is a combination of three antiretroviral medicines used for HIV infection. It prevents virus multiplication and boosts immunity.
Indications
- HIV-1 infection (in combination with other antiretrovirals)
Pharmacology
Lamivudine and Zidovudine are nucleoside analogues that are phosphorylated to active triphosphate metabolites and inhibit reverse transcription via DNA chain termination. Nevirapine binds directly to reverse transcriptase and disrupts the enzyme's catalytic site.
Dosage
Adult Dose (Oral):
- 1 tablet twice daily
- Only for patients who have tolerated the initial 200 mg once daily Nevirapine dose for 2 weeks
Renal Impairment: CrCl <50 mL/min: Avoid use
Side effects
Common Side Effects:
- Nausea
- Vomiting
- Diarrhea
- Headache
- Fatigue
- Insomnia
- Skin rash
- Muscle damage
- Anemia (low red blood cell count)
- Decreased white blood cell count (neutrophils)
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects on the fetus. Consult your doctor.
Precautions & warnings
- Monitor liver and kidney function regularly
- Avoid driving or activities requiring concentration (may cause fatigue and dizziness)
- Use effective contraception (medicine may cause birth defects)
- Avoid alcohol
- Do not stop suddenly
- Inform your doctor if you experience abdominal pain, loss of appetite, dark urine, or yellowing of eyes/skin
Overdose effects
No specific overdose information available; excessive doses may increase side effects.
Storage conditions
Store in a cool and dry place; keep out of reach of children.