৳ 0.54/unit
Pack: ৳ 0.54
৳ 0.54/unit
Pack: ৳ 0.54
At a glance
Diclofenac Sodium is an NSAID used for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, dysmenorrhea, and pain.
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Ankylosing spondylitis
- Acute gout
- Dysmenorrhea
- Post-traumatic and post-operative pain
- Renal and biliary colic
Pharmacology
Diclofenac Sodium is a potent NSAID with anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties. It inhibits cyclooxygenase, reducing prostaglandin synthesis.
Dosage
Adult (Oral - FC Tablet): 75-150 mg daily in 2-3 divided doses.
Adult (SR Tablet): 1 tablet daily (may increase to 150 mg/day if needed).
Adult (Dispersible Tablet): 2-3 tablets/day (max 150 mg/day).
Adult (Injection): 1 ampoule daily (2 ampoules/day in severe cases).
Adult (Suppository): 50 mg 2-3 times daily (max 150 mg/day).
Children: 1-3 mg/kg/day in divided doses.
Elderly: Lowest effective dose.
Side effects
Common: GI discomfort, epigastric pain, eructation, nausea, diarrhea, headache, dizziness.
Occasional: Skin rash, peripheral edema, serum transaminase abnormalities.
Rare: Peptic ulcer, haematemesis, melena, blood dyscrasia, anaphylactoid reactions.
Use in pregnancy
Pregnancy Category C. Avoid use of NSAIDs starting at 30 weeks of gestation; use in first trimester is inconclusive.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
History of GI ulceration, haematemesis, melena, ulcerative colitis, asthma, Crohn's disease, bleeding diathesis, severe hepatic/cardiac/renal insufficiency, hypertension. Monitor LFTs. May trigger attacks in hepatic porphyria.
Overdose effects
Treatment of overdose is symptomatic.
Storage conditions
Store in a cool and dry place, protected from light below 30°C. Keep out of reach of children.