Uteric40mg

• Fluid retention: associated with chronic congestive cardiac failure, acute congestive cardiac failure, chronic renal failure, nephrotic syndrome, and liver disease.
• Maintenance of fluid excretion in acute renal failure - including that due to pregnancy or burns.
• Hypertension
• Hypertensive crisis - as a supportive measure
• Support of forced diuresis

Adult Dose (Oral):

• Edema: Initial 40 mg daily, reduced to 20 mg daily or 40 mg on alternate days. Resistant edema: 80-120 mg daily. Severe cases: up to 600 mg/day.
• Hypertension: Initial 80 mg (usually 40 mg twice daily), adjust according to response.

Child Dose (Oral):

• Neonate: 0.5-2 mg/kg every 12-24 hours.
• 1 month-12 years: 0.5-2 mg/kg 2-3 times daily (max 12 mg/kg/day, not to exceed 80 mg/day).
• 12-18 years: 20-40 mg daily, resistant edema 80-120 mg daily.

Parenteral Dose:

• Adult: Initial 20-50 mg IM/IV, increase by 20 mg (every 2 hours).

Elderly: Slower elimination - titrate dosage.

* Use as directed by the registered physician

Common Side Effects:

• Dizziness
• Weakness
• Dehydration
• Decreased potassium level in blood
• Increased blood uric acid
• Decreased magnesium level in blood
• Increased thirst

With prolonged use: Electrolyte imbalance, alkalosis, hyperglycemia, glycosuria.

Precautions:

• Patients with prostatic hypertrophy or impairment of micturition have increased risk of acute retention.
• Marked fall in blood pressure may occur when ACE inhibitors are added.
• Toxic effects of nephrotoxic antibiotics may be increased.
• Driving or hazardous tasks - blood pressure reduction may impair concentration and reaction.