৳ 72/unit
Pack: ৳ 1,080
৳ 72/unit
Pack: ৳ 1,080
At a glance
Progesterone is a natural female sex hormone used for menstrual and pregnancy-related issues caused by hormonal imbalance, as a part of hormone replacement therapy for preventing endometrial hyperplasia, and for maintenance of pregnancy in women at higher risk of miscarriage.
Indications
- Progestogen component of menopausal hormone replacement therapy
- Amenorrhea
- Dysfunctional uterine bleeding
- Prevention of endometrial hyperplasia
- Maintenance of pregnancy in women at higher risk of miscarriage
Pharmacology
Progesterone is the main hormone secreted by the corpus luteum. It induces secretory changes in the endometrium, promotes mammary gland development, relaxes the uterus, blocks follicular maturation and ovulation, and maintains pregnancy.
Dosage
Adult Dose (Oral):
- Menopausal HRT: 200 mg daily as a single nightly dose for 12-14 days each month
- Amenorrhea: 400 mg daily for 10 days
- Dysfunctional uterine bleeding: 400 mg daily for 10 days
- Prevention of endometrial hyperplasia: 200 mg at night for 12 days per 28-day cycle
Vaginal Gel Dose:
- Dysfunctional uterine bleeding/Amenorrhea: 45 mg every other day from days 15-25 of the cycle; increase to 90 mg in non-responders
Side effects
Common Side Effects:
- Fatigue
- Sleepiness
- Headache
- Abdominal pain
- Nausea
- Bleeding or spotting between periods
Use in pregnancy
Use in Pregnancy: Safe during pregnancy; most studies have shown low or no risk to the developing baby.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May affect driving ability; do not drive if drowsy or dizzy
- Inform doctor if you have breast cancer, abnormal vaginal bleeding, or liver disease
- Pregnancy testing and uterine monitoring may be required
Overdose effects
No overdose information available; consult your doctor if taken in excess.
Storage conditions
Store in a cool and dry place; keep out of reach of children.