Valarux 500
Rx- Generic:
- Valacyclovir
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Tablet
- Pack size:
- Box (10 Tablet)
৳ 40.15/unit
Pack: ৳ 401.50
At a glance
Valacyclovir — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Valacyclovir is an antiviral medicine used in the treatment of herpes labialis, genital herpes infection and herpes zoster infections. It prevents the multiplication of virus in human cells and clears up the infection. Valacyclovir should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It may be taken with or without food, but it is better to take it at a fixed time. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage. It may lead to a few common side effects like headache, nausea and stomach pain. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding. Valacyclovir is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
Indications
• Herpes labialis • Genital herpes infection • Herpes zoster
Mechanism of action
Valaciclovir is the L-valine ester of aciclovir. A prodrug, it is rapidly converted to aciclovir by intestinal and hepatic metabolism. Aciclovir inhibits DNA synthesis and viral replication and has antiviral activity against herpes simplex virus types 1 (HSV-1) and 2 (HSV-2) and varicella-zoster virus.
Dosage
Adult Dose: Oral Herpes zoster (shingles) Adult: 1 g tid for 7 days. Immunocompromised patients: Continue treatment for a further 2 days after crusting of lesions. Herpes simplex infections of skin and mucous membranes; Genital herpes Adult: 500 mg bid for 3-5 days for recurrent episodes or up to 10 days for initial episodes. Immunocompromised patients: 1 g bid for at least 5 days for recurrent episodes or up to 10 days for initial episodes. Prophylaxis of cytomegaloviral infections in immunocompromised patients Adult: 2 g 4 times daily, begin as soon as possible post-transplant and usually continued for 90 days. Herpes labialis Adult: 2 g 12 hrly for 1 day. Suppression of recurrent herpes simplex Adult: 500 mg daily as a single or in 2 divided doses. Immunocompromised patients: 500 mg bid. Treatment is re-evaluated after 6-12 mth of therapy. Child Dose: Herpes simplex infections of skin and mucous membranes; Genital herpes Child: >12 yr: 500 mg bid for 3-5 days for recurrent episodes or up to 10 days for initial episodes. Immunocompromised patients: 1 g bid for at least 5 days for recurrent episodes or up to 10 days for initial episodes. Prophylaxis of cytomegaloviral infections in immunocompromised patients Child: >12 yr: 2 g 4 times daily, begin as soon as possible post-transplant and usually continued for 90 days. Herpes labialis Child: >12 yr: 2 g 12 hrly for 1 day. Suppression of recurrent herpes simplex Adult: Child: >12 yr: 500 mg daily as a single or in 2 divided doses. Immunocompromised patients: 500 mg bid. Treatment is re-evaluated after 6-12 mth of therapy. Chickenpox 2 years: 20 mg/kg PO q8hr for 5 days; not to exceed 1 g PO q8hr Renal Dose: Herpes labialis CrCl 30-49 mL/min: 1 g PO q12hr for 1 day CrCl 10-29 mL/min: 500 mg PO q12hr for 1 day CrCl <10 mL/min: 500 mg PO once Herpes zoster CrCl 30-49 mL/min: 1 g PO q12hr CrCl 10-29 mL/min: 1 g/day PO CrCl <10 mL/min: 500 mg/day PO Genital herpes (initial episode) CrCl 10-29 mL/min: 1 g/day PO CrCl <10 mL/min: 500 mg/day PO qDay Genital herpes (recurrent episodes)(suppressive therapy, immunocompetent patients) CrCl <29 mL/min: 500 mg/day PO
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valacyclovir may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Valacyclovir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Nausea • Abdominal pain
Precautions & warnings
[UNSAFE] Valacyclovir may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Do not skip any doses and finish the full course of treatment even if you feel better. Drink plenty of water while on treatment with this medicine. This helps to prevent dehydration and kidney damage. If you have genital herpes, use barrier methods (condoms) for contraception and avoid sexual contact while the sores are present. Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Contraindications
Hypersensitvity to valaciclovir, aciclovir.
Drug interactions
Increased risk of renal failure w/ nephrotoxic drugs (e.g. aminoglycosides, organoplatinum compounds, iodinated contrast media, methotrexate, pentamidine, foscarnet, ciclosporin, tacrolimus). Probenecid and cimetidine may increase peak plasma concentrations and AUC of aciclovir.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Valacyclovir. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Valacyclovir is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Valacyclovir is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Renal / hepatic impairment
[CAUTION] Valacyclovir should be used with caution in patients with kidney disease. Dose adjustment of Valacyclovir may be needed. Please consult your doctor. Drink plenty of water while you are taking this medicine to lower the side effects on the kidney. [SAFE IF PRESCRIBED] Valacyclovir is safe to use in patients with liver disease. No dose adjustment of Valacyclovir is recommended.
Common questions
Herpes zoster treatment on back Please tell me the right treatment Tab valcivir 1g tds for 5 daysMeanwhile visit skin specialist for proper examination and treatment Does valcivir 500 mg useful in harpies. What is harpies. yes valcivir is useful in herpies herpes is a viral infection of skin presents with blisters How to treat Herpes treatment sir?? Its came to me on sonta right side only, please help me sir Hello PATIENT a picture.Herpes simplex and herpes zoster r different and have different dosage Herpes zoster but there is lot of pain irritation n itching inspite of treatment from one month Not able to sleep at all Tab. Valcivir 1gram three times daily for 5 days. Tab. Pregaba M 75 twice daily for 1 week.Cap. Absolut DM once daily for 1 month. Fucidin cream for application twice daily. I've harpeas(nagin) on back and stomach due to which itching takes place which treatment and medicine should I use??? medicine is fine for herpes zoster . Complete the entire course Please suggest some medicines of canker sores or fever blister on mustache region Tablet or ointments etc. This is herpes labialisPlz visit for proper treatment meanwhile apply acivir gel twice a dayPlz visit for proper treatment Skin infection itching and rashaes jalan It seems herpes zoster, please visit skin specialist for proper examination and treatment Herpes zoster eye and skin manifestation since 1wk. If cornea is involved. . Antiviral treatment for eye is needed. . Visit ophthalmologist