Vancomin500mg

Vancomycin is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood and others. Vancomycin is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching. It may also be combined with other antibiotics to treat additional types of bacteria. Some people may develop local injection site reactions like pain, swelling, and redness. However, these are usually minor and temporary. Other side effects like wheezing, kidney (renal) injury, shortness of breath, flushing (sense of warmth in the face, ears, neck, and trunk) and decreased blood pressure may be seen occasionally. Inform your doctor if you have a history of an allergic reaction to this medication in the past. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Some people may be advised blood tests to check the level of this medicine in their blood. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. Vancomycin is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

• Severe bacterial infections

Vancomycin binds tightly to D-alanyl-D-alanine portion cell wall precursor causing blockage of glycopeptide polymerisation which produces immediate inhibition of cell wall synthesis and secondary damage to the cytoplasmic membrane.

Adult Dose: Intravenous Severe staphylococcal or other Gram-positive infections, Endocarditis Adult: 500 mg 6 hrly, infused over at least 60 min or 1 g 12 hrly, infused over at least 100 min. Elderly: Dosage adjustment needed. Child Dose: Intravenous Children Severe staphylococcal or other Gram-positive infections, Endocarditis 1 month: 10 mg/kg/day IV divided q6hr; individual dose not to exceed 1 g Renal Dose: Renal impairment: Patient on intermittent haemodialysis: Loading dose: 15-25 mg/kg on day 1, followed by 5-10 mg/kg maintenance dose after each dialysis run. Anuric patient (w/o kidney function) on dialysis: Initially, 15 mg/kg. Maintenance: 1.9 mg/kg 24 hrly. CrCl (ml/min) Dosage Recommendation 50 Initially, 15-20 mg/kg/dose (usual: 750-1,500 mg) 8-12 hrly.

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Breathlessness • Decreased blood pressure • Wheezing • Renal injury • Flushing (sense of warmth in the face, ears, neck and trunk)

[SAFE] Vancomycin does not usually affect your ability to drive. You have been prescribed Vancomycin to treat serious bacterial infections of the heart, blood, bones, and soft tissues. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat. It should be taken slowly via a drip. Fast infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Your doctor may get regular blood tests done to check the level of this medicine in your blood. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Hypersensitivity to the drug; history of impaired hearing; IM administration.

General anaesth may enhance the adverse effects of vancomycin. Increased risk of ototoxicity and nephrotoxicity w/ aminoglycosides, polymyxins, ciclosporin, cisplatin and loop diuretics. Increased potential of neuromuscular blockade w/ suxamethonium or vecuronium.

[SAFE] Consuming alcohol with Vancomycin does not cause any harmful side effects.

[CONSULT YOUR DOCTOR] Vancomycin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Vancomycin is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Vancomycin should be used with caution in patients with kidney disease. Dose adjustment of Vancomycin may be needed. Please consult your doctor. Regular monitoring of kidney function test and some blood tests is advised while you are taking this medicine. [CONSULT YOUR DOCTOR] There is limited information available on the use of Vancomycin in patients with liver disease. Please consult your doctor.

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