Vironex 1
OTC- Generic:
- Entecavir
- Company:
- Everest Pharmaceuticals Ltd.
- Dosage form:
- Tablet
- Pack size:
- Box (30 Tablet)
৳ 90/unit
Pack: ৳ 2,700
At a glance
Entecavir — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Entecavir is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection. Entecavir is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop. Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment. Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex. Entecavir is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
Indications
• Chronic hepatitis B virus (HBV) infection
Mechanism of action
Selective HBV DNA polymerase inhibitor; inhibition blocks reverse transcriptase activity, which in turn reduces viral DNA synthesis
Dosage
Adult Dose: Chronic Hepatitis B Indicated for treatment of CHB with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease Nucleoside inhibitor treatment-naïve with compensated liver disease (adults and adolescents ?16 yr): 0.5 mg PO qDay Lamivudine-refractory or known lamivudine or telbivudine resistance substitutions (adults and adolescents ?16 yr): 1 mg PO qDay Decompensated liver disease (adults): 1 mg PO qDay Child Dose: Chronic Hepatitis B Indicated for treatment of CHB with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease in children ?2 years and weigh at least 10 kg 16 years: As adult Renal Dose: Renal Impairment Usual daily dose (0.5 mg) CrCl ?50 mL/min: No dosage adjustment required CrCl 30-49 mL/min: Reduce to 0.25 mg/day or 0.5 mg q48hr CrCl 10-29 mL/min: Reduce to 0.15 mg/day or 0.5 mg q72hr CrCl <10 mL/min, hemodialysis, or CAPD: 0.05 mg/day or 0.5 mg q7days Lamivudine-refractory/decompensated liver disease daily dose (1 mg) CrCl ?50 mL/min: No dosage adjustment required CrCl 30-49 mL/min: Reduce to 0.5 mg/day or 1 mg q48hr CrCl 10-29 mL/min: Reduce to 0.3 mg/day or 1 mg q72hr CrCl <10 mL/min, hemodialysis, or CAPD: 0.1 mg/day or 1 mg q7days
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entecavir is to be taken empty stomach.
Missed dose
If you miss a dose of Entecavir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Headache • Dizziness • Tiredness • Nausea
Precautions & warnings
[UNSAFE] Entecavir may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Entecavir for the treatment of chronic hepatitis B virus (HBV) infection. Take it on an empty stomach, at least 2 hours after or before a meal. Entecavir may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. You may still develop infections or other illnesses associated with viral infection while taking this medication. During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.
Contraindications
Entecavir is contraindicated in patients with previously demonstrated hypersensitivity to Entecavir or any component of the product.
Drug interactions
Drugs that reduce renal function or compete for active tubular secretion may increase serum conc of either entecavir or co-administered drug.
Food interactions
[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Entecavir. Please consult your doctor.
Use in pregnancy
[CONSULT YOUR DOCTOR] Entecavir may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Use in lactation
[CONSULT YOUR DOCTOR] Entecavir is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[CAUTION] Entecavir should be used with caution in patients with kidney disease. Dose adjustment of Entecavir may be needed. Please consult your doctor. [SAFE IF PRESCRIBED] Entecavir is safe to use in patients with liver disease. No dose adjustment of Entecavir is recommended.
Common questions
I have HBV related chronic liver problem .Local urologist suggest me to take rapilif d 8 for urine block problem?Can i take that medicine with entavir for hepatitis b virus and cronic liver disease? Yes u can take it Suffering from Hepatitis B virus from last one week. Please suggest me. Pls consult a gastroenterologist How to treatment of HEPATITIS C VIRUS https://www.1mg.com/otc/himalaya-liv.-52-ds-tablet-otc135545One ?one tablet morning & evening after taking food , use at least 1-2 monthsUse this medicine along with your treatment Hepatitis b disise medicine's explain Hepatitis b disise medicine's explain https://www.1mg.com/otc/liv.52-hb-capsule-otc122387One ?one tablet morning & evening after taking food , use at least 1-2 monthsuse along with your treatment I'm suffering from hepatitis b virus. I want to ask what precautions should i take with my diet so that virus doesn't damage my liver first i would like to see your Hepatitis Profile test reports I am infected for hepatitis b virus. I am toke allopathy treatment. But I want take now ayurvedic treatment.please help me. Your case has to be seen in person before starting the treatment. What should be next course of action for me. Pls guide. I am about to be married and really scared. Dear PATIENT from 1mg. The reports shows positive Hepatitis B surface antigen which can be due to Hepatitis B infection. I suggest you should consult a Hepatologist/ Gatroenetrologist/ Physician for this. Fibro scan : median stiffness 3.3 kpa HBV DNA quantitative : target not detected PT -C 13 sec, T- 13.3 sec INR 1.03 Sir I want to know she is immune to HBV Or she is suffering from occult hepatitis b Need couple of tests more. Please see a gastroenterologist