Vitigo 30gm Cream1.5%
Rx- Generic:
- Ruxolitinib
- Company:
- Incepta Pharmaceuticals Ltd.
- Dosage form:
- Cream
- Pack size:
- 30gm tube
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৳ 6,500/unit
Pack: ৳ 6,500
Price comparison
- This brand
- ৳ 6500
- Cheapest of this genericVitigo 10gm Cream
- ৳ 2200
The cheaper brand costs ৳ 4300.00 less per unit
Compared against 5 brands
At a glance
Ruxolitinib is a JAK1/JAK2 inhibitor used for the treatment of myelofibrosis, polycythemia vera, and steroid-refractory acute graft-versus-host disease (GVHD). It modulates hematopoiesis and immune function by inhibiting JAK-STAT signaling pathways.
Indications
- Intermediate or high-risk myelofibrosis (primary MF, post-polycythemia vera MF, post-essential thrombocythemia MF)
- Polycythemia vera (inadequate response or intolerance to hydroxyurea)
- Steroid-refractory acute graft-versus-host disease (GVHD) – adults and pediatric patients ≥12 years
Dosage
Adult Dose (Oral):
Myelofibrosis (based on platelet count):
- >200 × 10⁹/L: 20 mg twice daily
- 100-200 × 10⁹/L: 15 mg twice daily
- 50-100 × 10⁹/L: 5 mg twice daily
Polycythemia Vera:
- Starting: 10 mg twice daily
Acute GVHD:
- Starting: 5 mg twice daily; increase to 10 mg twice daily after 3 days if ANC/platelets not decreased by ≥50%
Side effects
Common Side Effects:
- Thrombocytopenia
- Anemia
- Neutropenia
- Risk of infection
- Bruising
- Dizziness and headache
- Non-melanoma skin cancer
- Lipid elevations
Precautions & warnings
- Thrombocytopenia, anemia, neutropenia: Reduce dose or interrupt; monitor CBC every 2-4 weeks
- Risk of serious bacterial, mycobacterial, fungal, and viral infections
- Tuberculosis: Evaluate risk before starting; delay if active TB
- PML: Suspect, discontinue and evaluate
- Herpes zoster: Early signs and symptoms, seek treatment
- Hepatitis B: Monitor HBV-DNA titers
- Do not stop abruptly (withdrawal syndrome); taper gradually
- Non-melanoma skin cancer: Periodic skin examinations
- Lipids: Assess at 8-12 weeks
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.