Xeroder IV0.20%

• Oropharyngeal Candidiasis: Used for treatment of mouth and throat fungal infections.
• Esophageal Candidiasis: Used for treatment of esophageal fungal infections.
• Systemic Candidiasis: Used for treatment of blood and internal organ fungal infections.
• Cryptococcal Meningitis: Used for treatment of brain fungal infections.
• Prophylaxis: Used for prevention of fungal infections in immunocompromised patients.

Adult Dose (IV):

• Oropharyngeal Candidiasis: Day 1: 200 mg, then 100 mg daily (at least 2 weeks).
• Esophageal Candidiasis: Day 1: 200 mg, then 100 mg daily (up to 400 mg/day); at least 3 weeks.
• Systemic Candidiasis/Cryptococcal Infections: Day 1: 400 mg, then 200-400 mg daily; cryptococcal meningitis: 10-12 weeks.
• Bone Marrow Transplant Prophylaxis: 400 mg daily (start several days before neutropenia, continue 7 days after neutrophil count >1000).

Child Dose (IV):

• Oropharyngeal Candidiasis: Day 1: 6 mg/kg, then 3 mg/kg daily.
• Esophageal Candidiasis: 6 mg/kg Day 1, then 3 mg/kg daily (up to 12 mg/kg/day).
• Cryptococcal Meningitis: Day 1: 12 mg/kg, then 6 mg/kg daily.

Common Side Effects:

• Headache
• Nausea
• Rash
• Vomiting

Precautions:

• Fluconazole 0.2% IV may cause dizziness or seizures which may affect driving ability.
• Prescribed to cure infection and improve symptoms.
• Do not skip doses and finish the full course of treatment.
• Inform doctor if shortness of breath, swelling in face and throat, or drop in blood pressure occurs.
• Use a reliable method of contraception to prevent pregnancy while taking this medicine.
• Inform doctor if yellowing of eyes or skin, dark urine, or stomach pain occurs.
• Liver function may be checked before and during treatment.