Xevirol10mg
Rx- Generic:
- Everolimus
- Company:
- Beacon Pharmaceuticals PLC
- Dosage form:
- Tablet
- Pack size:
- Tablet
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At a glance
Everolimus is a kinase inhibitor used for prevention of organ rejection and treatment of breast, pancreatic, lung, and kidney cancers.
Indications
- Breast Cancer: Used in postmenopausal women with advanced hormone receptor-positive, HER2-negative breast cancer.
- Neuroendocrine Tumors: Used in pancreatic and GI/lung NET.
- Renal Cell Carcinoma: Used after sunitinib or sorafenib failure.
- Tuberous Sclerosis Complex (TSC): Used for renal angiomyolipoma and SEGA.
Dosage
Adult Dose (Oral):
- Breast Cancer, RCC, NET, Renal Angiomyolipoma: 10 mg once daily (with or without food).
- TSC-Associated SEGA: 4.5 mg/m² once daily (pediatric and adult) or tablet form dosing as per guidelines.
- TSC-Associated Partial-Onset Seizures: 5 mg/m² once daily.
Side effects
Common Side Effects (>=30%):
- Stomatitis
- Infections
- Rash
- Fatigue
- Diarrhea
- Edema
- Abdominal pain
- Nausea
- Fever
- Asthenia
- Cough
- Headache
- Decreased appetite
Precautions & warnings
Precautions:
- Everolimus may cause fatigue which may affect your ability to drive.
- Inform doctor if you have liver problems, diabetes, high cholesterol, recent surgery, or infection.
- Seek medical advice if you have increased thirst, increased urination, infection, shortness of breath, cough, or fever.
- Inform doctor before receiving any vaccination.
- Everolimus may affect male or female fertility; consult doctor if planning to have a child.
- Non-infectious pneumonitis: monitor symptoms.
- Infections: monitor symptoms; discontinue if severe.
- Angioedema: increased risk with ACE inhibitors.
- Wound healing: withhold 1 week before elective surgery; do not administer for 2 weeks after major surgery.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.