৳ 5.03/unit
Pack: ৳ 50.30
৳ 5.03/unit
Pack: ৳ 50.30
At a glance
Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, menstrual pain, muscle pain, and dental pain.
Indications
- Relief of signs and symptoms of osteoarthritis
- Rheumatoidal disorders (osseous rheumatism, ankylosing spondylitis, juvenile arthritis, muscular rheumatism, degenerative joint diseases)
- Acute symptomatic treatment of primary dysmenorrhoea
- Common headache and fever
- Symptomatic treatment of mild to moderate pain (muscle pain, headache, dental pain)
- Adjuvant with common cold and influenza associated with headache
Pharmacology
Dexibuprofen (S(+)-ibuprofen) is considered as the pharmacologically active enantiomer of racemic ibuprofen. Like racemic ibuprofen, Dexibuprofen is a non-steroidal anti-inflammatory drug with analgesic action. Dexibuprofen acts by inhibiting prostaglandin synthesis.
Dosage
Adult: 600-900 mg daily in 2-3 divided doses; may increase to 1200 mg daily for acute conditions (max 400 mg/dose, 1200 mg/day).
Dysmenorrhoea: 600-900 mg daily in 2-3 divided doses.
Elderly: Lowest effective dose; may increase to adult dose if well tolerated.
Hepatic/Renal impairment: Mild-moderate: start with low doses and monitor closely; severe: do not use.
Side effects
Common: Dyspepsia, diarrhea, fatigue, headache, nausea, vomiting, abdominal pain, hypersensitivity reactions, bleeding, ulcer.
Use in pregnancy
Pregnancy Category C. Dexibuprofen may be unsafe during pregnancy. Although no teratogenic impact observed in animal studies, use during late pregnancy should be avoided due to effects on fetal cardiovascular system.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
May affect driving ability (drowsiness, dizziness, visual disturbances). Avoid alcohol (increases risk of stomach problems). Do not take antacids within 2 hours of Dexibuprofen. Caution in heart disease, stroke, peptic ulcer, liver and kidney disease, bronchial asthma, allergy, systemic lupus or autoimmune disease.
Overdose effects
Dexibuprofen has low acute toxicity. Symptoms occur at 80-100 mg/kg. Mild symptoms: abdominal pain, nausea, vomiting, lethargy, headache, tinnitus, ataxia. Moderate-severe: flatulence, hypotension, hypothermia, metabolic acidosis, coma, apnoea. Treatment is symptomatic; no specific antidote. Activated charcoal; dialysis is of little value.
Storage conditions
Do not store above 30°C. Keep away from light and out of reach of children.