৳ 1,150/unit
Pack: ৳ 1,150
৳ 1,150/unit
Pack: ৳ 1,150
At a glance
Sertaconazole Topical is an imidazole antifungal cream used for the treatment of interdigital tinea pedis (athlete's foot) and other topical fungal infections. It kills fungi by inhibiting ergosterol synthesis in the fungal cell membrane.
Indications
- Interdigital tinea pedis (athlete's foot) caused by Trichophyton rubrum, T. mentagrophytes, Epidermophyton floccosum
- Other topical fungal infections (≥12 years, immunocompetent)
Pharmacology
Sertaconazole inhibits fungal cytochrome P450-mediated 14α-lanosterol demethylase, preventing ergosterol synthesis. Ergosterol is essential for fungal cell membrane integrity; its deficiency increases membrane permeability and causes fungal cell death.
Dosage
Adult Dose (Topical):
- Tinea pedis: Apply 2% cream twice daily to affected area and surrounding healthy skin for up to 4 weeks
Side effects
Common Side Effects:
- Contact dermatitis
- Dry skin
- Burning skin
- Application site tenderness
- Erythema, pruritus, vesiculation, desquamation, hyperpigmentation
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Safety and efficacy not established in children <12 years
- Discontinue treatment if irritation develops
- Cross-reactivity may occur with azole antifungals
- Inform doctor if infection does not clear within 4 weeks
Overdose effects
No overdose information available; excessive use may cause skin irritation; consult your doctor.
Storage conditions
Store below 25°C in a dry place, protected from light; keep out of reach of children.