Zapenia 25

Clozapine is a prescription medicine used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave). Clozapine may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include increased sweating, visual disturbance and decreased blood pressure. Please consult your doctor if these side effects do not get better or worse. Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson's disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems. Clozapine is an atypical antipsychotics. It works by modulating the action of certain chemical messengers in the brain that affects thoughts.

• Schizophrenia

Clozapine has relatively weak dopamine receptor-blocking activity at D1, D2, D3 and D5 receptors but has high affinity for the D4 receptor. It has also blocking effects on serotonin, ?-adrenergic histamine H1 and cholinergic receptors.

Adult Dose: Adults: PO: Schizophrenia 12.5 mg PO once daily or q12hr initially; increased daily in increments of 25-50 mg/day, if well tolerated, to achieve target dosage of 300-450 mg/day by end of 2 weeks On occasion, may have to be increased to 600-900 mg/day to obtain acceptable response Maintenance: Generally, patients who respond should continue maintenance treatment on their effective dose beyond the acute episode Psychoses in Parkinson's disease Initial: 12.5 mg/day at night, increase gradually in steps of 12.5 mg up to twice weekly. Usual range: 25-37.5 mg/day at bedtime. Max: 100 mg/day in 1-2 divided doses. Elderly: Lower initial dosage of 12.5-25 mg/day indicated; may be titrated more slowly than in younger adults Hepatic impairment: Use with caution and avoid in symptomatic or progressive liver disease or hepatic failure. Renal Dose: Renal impairment: Severe: Contraindicated.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clozapine may be taken with or without food, but it is better to take it at a fixed time.

Common: • Increased sweating • Visual impairment • Decreased blood pressure

[UNSAFE] Clozapine may cause side effects which could affect your ability to drive. You may feel tired, drowsy, dizzy or you may feel faint while taking ClozapineClozapine, especially during the early stages of treatment. This may affect your driving ability. Clozapine helps treat schizophrenia in people for whom other medicines are ineffective or not tolerated. Take it with or without food, preferably at the same time everyday. It can cause dizziness and sleepiness. Be cautious while driving or doing anything that requires concentration. It may cause low blood pressure and dehydration. Drink plenty of fluids and rise slowly from a sitting or lying position. It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly. Your doctor may get regular blood tests done to monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash. Do not stop taking Clozapine without talking to your doctor first as it may cause worsening of symptoms.

History of bone marrow disorders including agranulocytosis, circulatory collapse, alcoholic or toxic psychosis, drug intoxication, uncontrolled epilepsy, severe renal, hepatic or cardiac disease; paralytic ileus. Pregnancy and lactation.

Increased risk and/or severity of bone marrow suppression w/ bone marrow suppressants (e.g. carbamazepine, chloramphenicol), sulfonamides (e.g. co-trimoxazole), pyrazolone analgesics (e.g. phenylbutazone), penicillamine, cytotoxic agents or long-acting depot inj of antipsychotics. Concomitant use w/ benzodiazepines may increase risk of circulatory collapse which may lead to cardiac and/or resp arrest. Additive CNS depression and cognitive and motor performance interference w/ MAOIs and CNS depressants including antihistamines, benzodiazepines and opioid analgesics. May potentiate effects of anticholinergics or antihypertensives. Increased plasma concentration of highly protein bound substances (e.g. warfarin, digoxin). Decreased plasma concentrations w/ phenytoin. Concomitant use w/ lithium can increase the risk of development of neuroleptic malignant syndrome. Decreased clozapine levels w/ CYP1A2 inducers (e.g. omeprazole). Increased clozapine levels w/ CYP1A2 inhibitors (e.g. fluvoxamine, caffeine, ciprofloxacin).

[UNSAFE] It is unsafe to consume alcohol with Clozapine.

[SAFE IF PRESCRIBED] Clozapine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CONSULT YOUR DOCTOR] Clozapine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. If Clozapine is used, monitor the baby for excessive sedation. Periodically, keep a check on the baby's white blood cell count as well.

[CAUTION] Clozapine should be used with caution in patients with kidney disease. Dose adjustment of Clozapine may be needed. Please consult your doctor. Use of Clozapine is may not be advised in patients with severe kidney disease. [CAUTION] Clozapine should be used with caution in patients with liver disease. Dose adjustment of Clozapine may be needed. Please consult your doctor. Regular monitoring of liver function tests is advisable. Inform your doctor if you experience nausea, vomiting and/or weight loss while taking this medicine.

What is the use of sizopin tablet?? It's an antipsychotic, used to treat symptoms of psychosis. My son is having regular one sizopin 100 mg tab daily at bed time once for the last 3-4 years and test CBC examined half yearly.but his subconscious mind influences his mind misguided himself occasionally and controlled way.i need further suggestion from your side any to more improvement Sizopin is treatment for resistant schizophrenia. If your patient still has symptoms, the dose needs to be escalated or another anti psychotic needs to be added. How to treat erectile dysfunction with schizophrenia https://www.1mg.com/otc/himalaya-confido-tablet-otc90667One ?one tablet morning & evening after taking food , use at least 1-2 months Taking 100mg tablet in morning Which tablet for what Suhagra 100mg tablet have any side effect? all pills have side effects. if ur heart is fine its ok and for others google it. Hello Doctor, What is use of eating caverta 100mg tablet? Hello Vijaya it will increase sex time and long holding My wife was taking following medication for depression and mental disorder since 2004. Sizopin 50mg Serintin Nitrosun 10mg Unfortunately the doctor who was treating her passed away. These medicines were prescribed for life. In the absence of the Doctor should she continue the same medicines. Kindly advise. I think I responded to this issue yesterday. I reiterate that there are other psychiatrists available who are well versed with treatment of psychosis and use of clozapine. Visit another psychiatrist to continue treatment. I have been diagnosed with chlamydia pneumoniae Can u help me with the medication take tablet microdox dt 100mg 1 bd for 10 days