Zoletrust4mg/5ml

Zoledronic Acid 4mg is used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or use of steroids. Using this medicine can reduce your risk of breaking bones. It is also used to treat high levels of calcium in people who have cancer. Zoledronic Acid 4mg is given by a doctor or nurse. How much you are given, and how often, will be decided by your doctor. It may just be a single injection or you may need regular injections depending upon your underlying condition. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Zoledronic Acid 4mg is only part of a treatment program that may also include changes to your diet and taking calcium and vitamin supplements. The most common side effects include headache, flu-like symptoms, muscle pain and nausea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Zoledronic Acid 4mg can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills) or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away if you notice any of these. You should not be given this medicine if you are pregnant or breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also let your doctor know what other medicines you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and calcium levels. Avoid smoking as it can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided. Zoledronic Acid 4mg is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

• Osteoporosis • Hypercalcemia

Zoledronic acid, an aminobiphosphonate, is a potent inhibitor of bone resorption. It inhibits osteoclastic activity and skeletal calcium release caused by tumours.

Adult Dose: Intravenous Hypercalcaemia of malignancy Adult: 4 mg as a single dose by infusion over at least 15 minutes. Retreatment in patients who relapse or who are refractory to initial treatment: 4 mg as an infusion over at least 15 minutes, after at least 1 wk from initial dose. Bone metastases associated with solid tumours, Multiple Myeloma; Adult: 4 mg infusion over at least 15 minutes every 3-4 wk, in conjunction with 500 mg calcium and 400 IU vitamin D oral supplement. Patients with hepatic impairment Safety and efficacy not established Child Dose: Safety and efficacy not established Renal Dose: Renal impairment CrCl >60 mL/min: 4 mg CrCl 50-60 mL/min: 3.5 mg CrCl 40-49 mL/min: 3.3 mg CrCl 30-39 mL/min: 3 mg CrCl <30 mL/min: Not recommended

Your doctor or nurse will give you this medicine. Kindly do not self administer.

If you miss a dose of Zoledronic Acid 4mg. Please consult your doctor.

Common: • Headache • Back pain • Musculoskeletal (bone, muscle or joint) pain • Heartburn • Diarrhea

[UNSAFE] Zoledronic Acid 4mg may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Zoledronic Acid 4mg for the treatment of osteoporosis. It may also be used to treat high blood calcium levels (hypercalcemia) or bone damage and pain that may occur with cancer. It is given by injection into a vein, usually over at least 15 minutes or as directed by your doctor. Drink plenty of fluids to prevent dehydration and kidney damage. It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor. You may develop fever or flu like symptoms, such as chills, tiredness and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms. Zoledronic Acid 4mg may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw. Your doctor will monitor your response to Zoledronic Acid 4mg by testing your bone mineral density (BMD). This is usually done every 1-3 years. Do not take Zoledronic Acid 4mg if you are pregnant or breastfeeding.

The drug is contraindicated if patients have hypersensitivity to the active substance or to any of the excipients or to any bisphosphonates, hypocalcaemia, renal impairment (creatinine clearance <35 mL/min), current or recent uveitis, or a history of bisphosphonate-associated uveitis, pregnancy and lactation.

Increased risk of hypocalcaemia with aminoglycosides and loop diuretics. Increased risk renal dysfunction with nephrotoxic agents.

[CAUTION] Caution is advised when consuming alcohol with Zoledronic Acid 4mg. Please consult your doctor.

[CONSULT YOUR DOCTOR] Zoledronic Acid 4mg is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[CONSULT YOUR DOCTOR] Zoledronic Acid 4mg is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Zoledronic Acid 4mg in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Zoledronic Acid 4mg in patients with liver disease. Please consult your doctor.

Teriparatide is this injection advisable? Yes, it&#x27;s good in Osteoporosis Me grand mother is suffering from vomiting and loose motion. So we gave her domstal 10 mg but immediately after giving she vomitted give him injection Ondem 4mg Have done vomiting 3-4 times after wake up The teeth feeling like acidic while vomiting take injection Ondem 4mg 1 vial For continuous vomiting from last night ondem injection IM slowlyor Ondem 4mg twice a day Skin problem. Tricort table 4mg is enough or i need injection of 10 mg. Its etching very much Continue the treatment advised by your doctorFlutivate cream apply three to four times I am suffering osteoporosis since 9 years. I came to know that without knee joint replacement, have another option I.e halonix injection treatment. So please can u give about injections treatment in detail It is a newer option with good results in early stages of Osteoarthritis Suffering from acute stomach pain with loose motion and vomiting Need to admit in hospitalGive her Ondem 4mg iv injectionGive her also one ors sachet to be mixed in 1 litre water and to be drink in 4-6 hour Osteoporosis I am using terifrac 750mg injection for past 5months still I could not see any difference i am suffering from back pain for 6years Hi kindly share your any reports which you have done