৳ 75/unit
Pack: ৳ 300
৳ 75/unit
Pack: ৳ 300
At a glance
Valacyclovir is an antiviral medicine used in the treatment of herpes labialis, genital herpes infection, and herpes zoster infections. It prevents the multiplication of virus in human cells and clears up the infection.
Indications
- Herpes labialis
- Genital herpes infection
- Herpes zoster
- Ophthalmic zoster
- Herpes simplex virus infections
- Cytomegalovirus (CMV) infection prophylaxis
Pharmacology
Valaciclovir is the L-valine ester of aciclovir. A prodrug, it is rapidly converted to aciclovir by intestinal and hepatic metabolism. Aciclovir inhibits DNA synthesis and viral replication.
Dosage
Adult Dose (Oral):
- Herpes zoster: 1 g three times daily for 7 days
- Genital herpes (initial): 1 g twice daily for 10 days
- Genital herpes (recurrent): 500 mg twice daily for 3-5 days
- Herpes labialis: 2 g twice daily for 1 day
- Herpes simplex suppression: 500 mg once daily
- CMV prophylaxis: 2 g four times daily
Child Dose (>12 years): Same as adult dose
Renal Impairment: Dose adjustment based on creatinine clearance
Side effects
Common Side Effects:
- Headache
- Nausea
- Abdominal pain
- Diarrhea
- Vomiting
- Dizziness
- Confusion
- Hallucinations
- Rash
- Pruritus
- Renal pain
- Renal impairment
Use in pregnancy
Use in Pregnancy: Generally considered safe; animal studies show low or no adverse effects; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May decrease alertness; do not drive
- Drink plenty of water during treatment; helps prevent dehydration and kidney damage
- If you have genital herpes, use barrier methods (condoms) and avoid sexual contact while sores are present
- Consult doctor if pregnant or breastfeeding
Overdose effects
Symptoms: Acute renal failure and neurological symptoms (confusion, hallucinations, agitation, decreased consciousness, coma), nausea and vomiting.
Treatment: Observe closely for signs of toxicity; hemodialysis significantly enhances removal of aciclovir.
Storage conditions
Store in a cool & dry place, away from children.