Zulfidin 500

Sulfasalazine is a medicine used to treat various inflammatory conditions of the joints (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis), skin (psoriasis), and bowel (ulcerative colitis, Crohn’s disease). Sulfasalazine is to be taken with food. This will help you prevent an upset stomach. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. Taking it with plenty of water can help you avoid kidney problems such as kidney stones. Using this medicine may cause some common side effects such as nausea, headache, loss of appetite, vomiting, diarrhea, weight loss, and gastrointestinal discomfort. You should consult with your doctor if any of these side effects do resolve with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problem with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular blood tests to check your kidney and liver functions, and blood components. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine. Sulfasalazine is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

• Rheumatoid arthritis • Ulcerative colitis • Crohn’s disease • Ankylosing spondylitis

Actual mechanism not determined. Sulphasalazine may have direct anti-inflammatory action in the colon. It also systemically interferes with secretion by prostaglandin synthesis inhibition.

Adult Dose: Oral Inflammatory bowel disease Adult: Initially, 1-2 g 4 times daily until remission occurs. Maintenance: 2 g/day in divided doses. Rheumatoid arthritis Adult: As enteric-coated tablet: Initially, 500 mg daily for the 1st wk increased by 500 mg every wk. Max: 3 g daily in 2-4 divided doses. Rectal Inflammatory bowel disease Adult: As suppository: 0.5-1 g in the morning and night, either alone or as an adjunct to oral treatment. Hepatic impairment: Avoid use. Child Dose: Oral Inflammatory bowel disease Child: >2 yr: 40-60 mg/kg/day in divided doses. Maintenance: 20-30 mg/kg/day in divided doses. Rheumatoid arthritis Child: For polyarticular juvenile rheumatoid arthritis: >6 yr: As enteric-coated tablet: 30-50 mg/kg/day in 2 divided doses. Begin treatment with 1/4 to 2/3 of expected maintenance dose and increase wkly to reach maintenance dose in 1 mth. Max: 2 g daily. Rectal Inflammatory bowel disease Child: As suppository (may be given as divided doses): 5-8 yr: 500 mg bid; 8-12 yr: 500 mg in the morning and 1 g at night; 12-18 yr: 1 g bid. Renal Dose: Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30ml/min Admin twice daily. <10ml/min Admin once daily.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sulfasalazine is to be taken with food.

If you miss a dose of Sulfasalazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Diarrhea • Gastrointestinal discomfort • Headache • Loss of appetite • Nausea • Oligospermia (low sperm count) • Vomiting • Weight loss

[SAFE] Sulfasalazine does not usually affect your ability to drive. Take it with food to avoid an upset stomach. It may take 6-8 weeks for Sazo 500 Tablet DR to work. Keep taking it as prescribed. Drink plenty of fluids while taking Sazo 500 Tablet DR in order to avoid kidney problems such as kidney stones. It may cause a deficiency of folic acid. Take the supplements as suggested by the doctor. Do not take Sazo 500 Tablet DR if you are allergic to sulfa drugs or aspirin. It may discolour your skin, urine, saliva and tears an orange/yellow colour. This is normal and not harmful. Regular blood tests to monitor your liver function, kidney function, and the levels of your blood components are required while taking this medicine. Do not stop taking the medication suddenly without talking to your doctor.

Hypersensitivity to sulphonamides or salicylates, porphyria, <2 yr of age, intestinal or urinary obstruction, blood dycrasias, history of leucopenia with gold therapy.

Plasma levels reduced by rifampicin and ethambutol. Interferes with absorption of folic acid. Additive leucopaenia with gold therapy for rheumatoid arthritis. Increased haematological toxicity with azathioprine. Reduced serum levels of digoxin.

[UNSAFE] It is unsafe to consume alcohol with Sulfasalazine.

[SAFE IF PRESCRIBED] Sulfasalazine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CONSULT YOUR DOCTOR] Sulfasalazine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[CAUTION] Sulfasalazine should be used with caution in patients with kidney disease. Dose adjustment of Sulfasalazine may be needed. Please consult your doctor. Regular monitoring of kidney function tests is advisable while you are taking this medicine. [UNSAFE] Sulfasalazine is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Having severe ankylosing spondylitis Sazo 1000 mg along with calcijoint tab one perday going on. Still problem persists. Please suggest more on this Take sazo twice dailyAnd take Tab Tolpazen twice daily for 5 daysApply Dynapar QPS spray Suffering from severe lower back pain since 6 years. As per MRI it is lumbar spondylosis,but Doctor told that it is one of the types of arthritis in which bridge is getting formed on spine Is there any permanent solution .at present taking Sazo 500 twice a day It&#x27;s called Ankylosing spondylitis". no permanent cure for this All you need to do is to exercise each and every joint of your body regularly "Along with the medication I have HLA B26 positive report and suffering from acute hip joint pain. I an taking sazo 500mg and Myotop DSR 1 tab daily. How long i hav to take the pills and will it cure me. still there pains and stiffness many times. You have Ankylosing Spondylitis" It is an auto-immune Disease and cannot be cured Medicine helps to reduce the symptoms "You need to exercise each and every joint of your body daily.Get a Digital x-ray done of Both hips(AP view) and share it Rheumatoid arthritis diseases attack Rheumatoid arthritis diseases tablet for this please consult rheumatologist for the same Suffering from ultratics colitis i have done colonoscopy test 04 months back From 05 months how many months I have to take medicines is it cure completely Ulcerative colitis is a lifelong disease with remission and exacerbations. Durations of remission cant b predicted all d time I have ulcerative colitis. Need treatment https://goo.gl/forms/5QhDt8ZurRhhcjvD2 Kindly fill the health information so that I can advice best products to you thankshttps://www.1mg.com/otc/jiva-digestol-tablet-otc329948One ?one tablet morning & evening after taking food , use at least 1-2 monthsTake buttermilk in lunch timeAvoid taking milk & milk Product Hi, I was diagnosed for Ulcerative Colitis in 2009. I was administered with Mesacol , I was back to normal. In past 1 month , after having food lunch or dinner I feel uneasy such as indigestion, having to force for motions next day. Sometimes Iam unable to pass motions. I feel tired also. Pls suggest. Ulcerative colitis is a lifong disease q with remission and exacerbation . U should b under constant follow up of ur gastroenterologist i m suffering from ankylosing spondylitis. best suggestions to reduce symptom Along with above Treatment and Exercises take Tab Saaz-500 twice daily for 1 month