Generic
Allantoin
1 brands available in the market
At a glance
Cell proliferant and anti-scar topical gel indicated for the treatment of hypertrophic, keloid, surgical, burn, and trauma scars.
Description
Allantoin gel is an anti-scar formulation containing Allantoin and Allium Cepa extract that stimulates cell proliferation, accelerates epithelization, and prevents non-physiological scar formation.
Indications
Indicated for hypertrophic and keloid scars, surgical scars, burn scars, trauma scars, and traumatic tendon contractures.
Therapeutic class
Topical Skin Preparation, Anti-scar Formulation
Pharmacological class
Cell Proliferant & Anti-scar Agent
Pharmacology
Allantoin stimulates cell growth and epithelization while providing skin elasticity. Allium cepa extract exerts anti-inflammatory, anti-allergenic, and bactericidal properties that inhibit keloidal fibroblast proliferation.
Mechanism of action
Promotes healthy cell regeneration and inhibits excessive fibroblast proliferation to prevent abnormal scar tissue formation.
Dosage
Apply once daily for at least 8 weeks on new scars and for 3-6 months on existing scars until fully absorbed.
Administration
Topical use only. Apply after wound closure and removal of stitches. Avoid contact with eyes and mucous membranes.
Missed dose
Apply as soon as remembered.
Side effects
Generally well tolerated. Rare local irritation such as slight erythema or itching may occur.
Precautions & warnings
For external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes.
Contraindications
Contraindicated in patients with known hypersensitivity to any of the ingredients.
Drug interactions
No known interactions with other medications.
Food interactions
Not applicable for topical formulation.
Use in pregnancy
No adequate studies conducted; use with caution during pregnancy.
Pregnancy Category: N/A — always consult a doctor before taking during pregnancy.
Use in lactation
Use with caution during lactation.
Pediatric use
Safe and tolerable in children from 6 months of age.
Geriatric use
Safe for use in elderly patients.
Renal / hepatic impairment
No dose adjustments required for renal or hepatic impairment.
Overdose effects
Unlikely via topical route. Seek medical attention if accidentally ingested.
Storage conditions
Do not store above 30°C. Keep away from light and out of reach of children.
Chemical structure
Allantoin (C4H6N4O3)