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Benzydamine Mouth prep

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At a glance

Benzydamine Mouth prep is a pain relieving and anti-inflammatory medicine used to relieve pain, discomfort, and inflammation of the mouth, gums, and throat.

Description

Benzydamine Mouth prep is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, discomfort, and inflammation of the mouth, gums, and throat. It works by inhibiting the synthesis of pro-inflammatory cytokines like TNF-α and IL-1β, and also has a local anesthetic effect by inhibiting the release of inflammatory mediators like substance P.

This medicine is used as a mouthwash or gargle. It should be spat out after use, not swallowed. It can be diluted with water if stinging occurs. Avoid contact with eyes.

Indications
  • Mouth/Throat Pain or irritation
  • Acute pharyngitis
  • Radiation-Associated Mucositis
Therapeutic class

Topical NSAIDs

Pharmacological class

Non-Steroidal Anti-Inflammatory Drug (NSAID)

Pharmacology

Benzydamine Hydrochloride predominantly acts by inhibiting the synthesis of pro inflammatory cytokines like tumour necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) without largely affecting other pro inflammatory cytokines. Moreover, it is capable of a local anaesthetic effect that may be related to its capability for inhibiting the release of inflammatory mediators like substance P.

Mechanism of action

Benzydamine inhibits the synthesis of pro-inflammatory cytokines (TNF-α and IL-1β) to reduce inflammation and provides local pain relief by inhibiting the release of inflammatory mediators like substance P.

Dosage

Mouth/Throat Pain, Acute pharyngitis: Rinse or gargle 15 ml of a 0.15% solution every 1½ to 3 hours until remission of pain (dilute with water if stinging occurs).

Radiation-Associated Mucositis: Gargle or rinse 15 mL in mouth (for 30 seconds, followed by expulsion) 3-4 times per day. Begin treatment 1 day prior to radiation therapy and continue daily during treatment.

Administration

Check the label before use. Take the mouthwash in the quantity as advised by your doctor and put it in your mouth. Swish for 30 seconds to 1 minute and spit it out. Do not swallow. Avoid eating, drinking, or smoking for at least 30 minutes after rinsing.

Missed dose

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects
  • No common side effects seen
  • Mild burning sensation at application site (temporary)
Precautions & warnings
  • For mouth rinse or gargle only
  • Spit the rinse out after use, do not swallow it
  • Should generally be used undiluted; if it stings, dilute with an equal volume of water
  • Avoid getting it in your eyes
  • Do not use for more than seven days unless otherwise advised by your doctor
  • Caution during pregnancy and lactation
Contraindications
  • Hypersensitivity to benzydamine hydrochloride or any component
Drug interactions

No significant drug interactions are known.

Food interactions

No food-related restrictions.

Use in pregnancy

[SAFE IF PRESCRIBED] Benzydamine Mouth prep is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[CONSULT YOUR DOCTOR] Information regarding the use of Benzydamine Mouth prep during breastfeeding is not available. Please consult your doctor.

Pediatric use

Use as directed by a physician for children.

Geriatric use

No dose adjustment needed for elderly patients.

Renal / hepatic impairment

Systemic absorption with topical application is minimal, so no dosage adjustment is needed for renal or hepatic impairment.

Overdose effects

Overuse may cause local irritation. Consult a doctor if symptoms occur.

Storage conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.

Chemical structure

Benzydamine Hydrochloride

Common questions

What is Benzydamine Mouth prep?
Benzydamine Mouth prep is a pain relieving and anti-inflammatory medicine used for pain and inflammation of the mouth, gums, and throat.
How should Benzydamine Mouth prep be used?
It is used as a mouthwash or gargle. Take the prescribed amount, swish for 30 seconds to 1 minute, and spit it out. Do not swallow.
What are the side effects?
No significant side effects are commonly seen. Mild burning sensation may occur at the application site.
Is Benzydamine Mouth prep safe during pregnancy?
It is generally considered safe during pregnancy. However, consult your doctor before use.
How long should Benzydamine Mouth prep be used?
Do not use for more than seven days unless advised by your doctor.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.