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Calcium Chloride + Dextrose Anhydrous + Potassium Chloride IV Infusion

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At a glance

Calcium Chloride + Dextrose Anhydrous + Potassium Chloride IV Infusion is an electrolyte and fluid replenisher used in hypovolemia caused by trauma, surgery, hemorrhage, and burns. It serves as a source of water, electrolytes, and calories.

Description

Calcium Chloride + Dextrose Anhydrous + Potassium Chloride IV Infusion is a sterile solution used for fluid and electrolyte replenishment in hypovolemia caused by trauma, surgery, hemorrhage, and burns. It serves as a source of water, electrolytes, and calories.

Calcium Chloride prevents and treats negative calcium balance and facilitates nerve and muscle function. Potassium Chloride is a major cation of intracellular fluid, playing a role in nerve impulse conduction in the heart, brain, and skeletal muscle. Dextrose provides calories and water for hydration, reduces protein and nitrogen loss, and promotes glycogen deposition in the liver.

Indications
  • Hypovolemia (caused by trauma, surgery, hemorrhage, and burns)
  • Fluid and electrolyte replenishment
  • Source of water, electrolytes, and calories
Therapeutic class

Intravenous Fluid Therapy

Pharmacological class

Electrolyte & Fluid Replenisher

Pharmacology

Calcium Chloride prevents or treats negative calcium balance and regulates action potential excitation threshold to facilitate nerve and muscle performance. Potassium Chloride is a major cation of intracellular fluid, playing an active role in nerve impulse conduction in the heart, brain, and skeletal muscle, and in muscle contraction. Dextrose is a monosaccharide that provides calories and water for hydration, reduces protein and nitrogen loss, and promotes glycogen deposition in the liver.

Mechanism of action

When administered intravenously, this solution provides calcium, potassium, and dextrose to the body, replenishing essential electrolytes and fluids while providing energy.

Dosage

Adults: Generally administered at 30-75 drops/min IV infusion.

Note: Dose and infusion rate are determined based on the patient's clinical condition, age, and physician's advice.

Administration

For IV infusion only. Administered by healthcare professionals. Patient should not self-administer.

Missed dose

Hospital-only medicine. Administered by doctor or nurse. Missed dose concept does not apply (hospital-administered).

Side effects

Infusion-related reactions: Febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, hypervolemia.

Precautions & warnings
  • Do not use if the solution is cloudy, contains particles, or is expired.
  • Infusion should be immediately discontinued if rigor occurs for any reason during the process.
  • Monitor the patient's condition and response during infusion.
Contraindications
  • Known allergy to corn or corn products (for dextrose-containing solutions)
  • Severe hypercalcemia
  • Severe hyperkalemia
Drug interactions
  • Insulin: When used with dextrose, insulin stimulates potassium uptake by cells, especially in muscle tissue, lowering serum potassium levels.
  • Digitalis glycosides: Calcium may precipitate digitalis toxicity in hypercalcemia; caution required.
Food interactions

No food-related restrictions (parenteral administration).

Use in pregnancy

Adequate information on use during pregnancy is not available; consult your doctor.

Use in lactation

Adequate information on use during lactation is not available; consult your doctor.

Pediatric use

Use in children under medical supervision with appropriate dose and infusion rate.

Geriatric use

Elderly patients require careful dose determination considering cardiac and renal function.

Renal / hepatic impairment
Renal impairment: Use with caution with monitoring of potassium and calcium levels.

Hepatic impairment: Caution required in liver disease; consult your doctor.
Overdose effects

Overdose symptoms: Hypervolemia, electrolyte imbalance (hypercalcemia, hyperkalemia), hyperglycemia. Consult your doctor immediately if overdose is suspected.

Storage conditions

Store below 30°C, away from light. Keep out of reach of children.

Chemical structure

Calcium Chloride + Dextrose Anhydrous + Potassium Chloride

Common questions

What is this infusion used for?
It is used for fluid and electrolyte replenishment in hypovolemia caused by trauma, surgery, hemorrhage, and burns.
How is it administered?
Generally administered at 30-75 drops/min as an IV infusion.
What are the side effects?
Febrile response, infection at injection site, venous thrombosis, phlebitis, extravasation, hypervolemia may occur.
Who should not use this infusion?
Patients with allergy to corn or corn products, severe hypercalcemia, or severe hyperkalemia should not use it.
When should the solution not be used?
Do not use if the solution is cloudy, contains particles, or is expired.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.