Generic
Calcium Chloride + Potassium Chloride + Sodium Chloride Injection
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At a glance
Calcium Chloride + Potassium Chloride + Sodium Chloride Injection is a combination of three mineral salts used for short-term fluid replacement after trauma. It helps replenish the body's fluid and electrolytes.
Description
Calcium Chloride + Potassium Chloride + Sodium Chloride Injection is a combination of three mineral salts used for short-term fluid and electrolyte replacement after trauma, surgery, or other conditions. Calcium Chloride, Potassium Chloride, and Sodium Chloride work together to replenish the body's fluid and electrolytes, preventing dehydration.
Calcium Chloride prevents and treats negative calcium balance and facilitates nerve and muscle function. Potassium Chloride is a major cation of intracellular fluid, playing a role in nerve impulse conduction in the heart, brain, and skeletal muscle. Sodium Chloride is the major extracellular cation important for electrolyte and fluid balance and osmotic pressure control.
Indications
- Short-term fluid replacement after trauma
Therapeutic class
Intravenous Fluid Therapy
Pharmacological class
Electrolyte & Fluid Replenisher
Pharmacology
Calcium Chloride prevents or treats negative calcium balance and regulates action potential excitation threshold to facilitate nerve and muscle performance. Potassium Chloride is a major cation of intracellular fluid, playing an active role in nerve impulse conduction and muscle contraction. Sodium Chloride is the major extracellular cation important for electrolyte and fluid balance and osmotic pressure control.
Mechanism of action
Calcium, potassium, and sodium chloride together provide essential electrolytes and fluid to the body, preventing dehydration and maintaining nerve and muscle function.
Dosage
Adults: Dose and infusion rate are determined based on the patient's clinical condition and physician's advice.
Note: This injection should be administered by a healthcare professional only.
Administration
For IV infusion only. Administered by healthcare professionals. Patient should not self-administer.
Missed dose
Hospital-only medicine. Administered by doctor or nurse. Missed dose concept does not apply (hospital-administered).
Side effects
Common side effects: Injection site reactions (redness, pain, swelling).
Other: Electrolyte imbalance, hypercalcemia, hyperkalemia (if given in excessive doses).
Precautions & warnings
- For hospital use only, administered by healthcare professionals.
- Use with caution in severe kidney disease; dose adjustment may be needed.
- Monitor the patient's electrolyte and fluid balance during infusion.
- Caution during pregnancy and lactation.
Contraindications
- Severe hypercalcemia
- Severe hyperkalemia
- Hypersensitivity to any of the ingredients
Drug interactions
- Digitalis glycosides: Calcium may precipitate digitalis toxicity in hypercalcemia; caution required.
- Potassium-sparing diuretics: Increased risk of hyperkalemia.
Food interactions
It is not known whether it is safe to consume alcohol with this injection; please consult your doctor.
Use in pregnancy
May be unsafe during pregnancy. Limited human studies available; animal studies have shown harmful effects on the developing baby. Consult your doctor.
Use in lactation
Adequate information on use during lactation is not available; consult your doctor.
Pediatric use
Use in children under medical supervision with appropriate dose and infusion rate.
Geriatric use
Elderly patients require careful dose determination considering cardiac and renal function.
Renal / hepatic impairment
Hepatic impairment: Probably safe; dose adjustment may not be needed.
Overdose effects
Overdose symptoms: Electrolyte imbalance (hypercalcemia, hyperkalemia), fluid overload. Consult your doctor immediately if overdose is suspected.
Storage conditions
Store below 30°C, away from light. Keep out of reach of children.
Chemical structure
Calcium Chloride + Potassium Chloride + Sodium Chloride