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Carboxymethylcellulose Sodium Eye Prep

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At a glance

Carboxymethylcellulose Sodium Eye Prep is an ocular lubricant used to relieve irritation and discomfort due to dryness of the eye or exposure to wind or sun. It lubricates the surface of the eye similarly to natural tears.

Description

Carboxymethylcellulose Sodium is an ocular lubricant that relieves dryness and irritation of the eye. It is a polymer in nature and is a clear, colorless aqueous solution. This medication lubricates the surface of the eye in the same way as natural tears.

It relieves dry eye symptoms in two ways: firstly by providing a lubricating and hydrating protective shield on the ocular surface, and then by working below the tear film to provide protection to the cornea.

It is effective in alleviating symptoms seen in moderate to severe dry eye syndromes (DES) and provides long-lasting protection against dryness and irritation. The pharmacological effect is not receptor-mediated but is due to its property as a viscosity enhancer, resulting in increased retention time of the eye drop.

Indications
  • Dry eyes
  • Irritation and discomfort due to exposure to wind or sun
Therapeutic class

Ophthalmic Lubricant

Pharmacological class

Artificial Tear / Ocular Lubricant

Pharmacology

Carboxymethylcellulose Sodium is an ocular lubricant that provides a lubricating and hydrating protective shield on the ocular surface similar to natural tears and works below the tear film to protect the cornea. Its action is not receptor-mediated but is due to its viscosity-enhancing properties that increase the retention time of the eye drop.

Mechanism of action

Carboxymethylcellulose Sodium forms a lubricating film on the ocular surface that mimics natural tears and protects the cornea.

Dosage

Adults: Instill 1-2 drops in the affected eye(s) up to 4 times daily as needed.

Children (under 3 years): Do not use.

Elderly: No overall differences in safety or effectiveness have been observed between elderly and other adult patients.

Note: Apply pressure on the inner corner of the eye for 2 minutes after instillation (to reduce systemic absorption).

Administration
Instructions for use:
1. Open the bottle by turning the cap.
2. Tilt your head back, pull the lower eyelid down, and place 1 drop into the eye.
3. Close your eye and press the inner corner of the eye with your finger for about 2 minutes.
4. Recap the bottle after each use.

Remove contact lenses before using. Allow at least 5 minutes between different eye medications (15 minutes for preservative-free liquigel). Use within 30 days of opening (60 days for preservative-free liquigel).
Missed dose

If you miss a dose, apply it as soon as you remember. Skip the missed dose if it is almost time for your next dose. Do not double the dose.

Side effects
  • Temporary blurred vision upon first use
  • Minor burning/stinging/irritation (temporary)
  • Eye irritation, pruritus, ocular discharge, visual disturbance (rare)
Precautions & warnings
  • For external use only.
  • Do not use if the solution changes color or becomes cloudy.
  • Do not touch the dropper tip to any surface (to avoid contamination).
  • Remove contact lenses before applying drops.
  • Allow at least 5 minutes between different eye medications (15 minutes for preservative-free liquigel).
  • Consult your doctor before use during pregnancy and lactation.
Contraindications
  • Known hypersensitivity to any ingredient
Drug interactions

If several eye medications are used, allow at least 5 minutes between each application (15 minutes for preservative-free liquigel).

Food interactions

No food-related restrictions (topical application).

Use in pregnancy

Safe use during pregnancy has not been established; consult your doctor before use if pregnant.

Use in lactation

Safe use during lactation has not been established; consult your doctor before use if breastfeeding.

Pediatric use

Do not use in children under 3 years. Use in children 3 years and older under medical supervision.

Geriatric use

No overall differences in safety or effectiveness have been observed between elderly and other adult patients.

Renal / hepatic impairment

No special precautions required for patients with liver or kidney impairment (minimal systemic absorption with topical application).

Overdose effects

Overuse may cause temporary blurred vision or irritation. Consult your doctor if symptoms persist.

Storage conditions

Store below 30°C in a dry place, protected from light. Use within 30 days of opening (60 days for preservative-free liquigel). Keep out of reach of children.

Chemical structure

Carboxymethylcellulose Sodium

Common questions

What is Carboxymethylcellulose Sodium Eye Prep used for?
It is used to relieve dry eyes, irritation, and discomfort due to exposure to wind or sun.
How should I use it?
Instill 1-2 drops in the affected eye(s) up to 4 times daily as needed.
What are the side effects?
Temporary blurred vision or minor burning/stinging may occur upon first use.
What about contact lenses?
Remove contact lenses before applying drops and wait at least 15 minutes before reinserting.
How long can I use it?
Use within 30 days of opening (60 days for preservative-free liquigel).
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.