Generic
Ciclopirox Topical
10 brands available in the market
At a glance
Ciclopirox Topical is an antifungal medication used for the treatment of fungal skin and nail infections.
Description
Ciclopirox Topical is an antifungal medication. It is used in the treatment of fungal skin and nail infections. It works by stopping the growth of fungi, thus treating the infection. Ciclopirox Topical is for external use only. You should use it in the dose and duration as directed by your doctor. The amount you need, and how long you take it will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of the medicine. You should avoid getting in contact with your mouth, eyes and nose. In case of accidental contact, wash it off with plenty of water. Keep using it regularly to get the most benefit. The most common side effects include itching, burning or stinging sensation at the site of application. They are not usually serious and often disappear with time.
Ciclopirox Topical is an antifungal medicine. It stops protein production in the fungal cells disrupting the cell division process. This is how it prevents further growth of fungi and helps to treat your skin and nail infections.
Indications
- Fungal skin infections
- Fungal nail infections (Onychomycosis)
- Seborrheic dermatitis
Therapeutic class
Antifungals (Topical)
Pharmacological class
Topical Antifungal (Pyridone Derivative)
Pharmacology
Ciclopirox has a wide spectrum of antifungal activity and some antibacterial activity. Inhibits most Candida, Epidermophyton, Microsporum, Trichophyton species and M. furfur by inhibiting transport of essential elements in fungal cells, thus disrupting DNA, RNA and protein synthesis.
Mechanism of action
Ciclopirox inhibits the transport of essential elements in fungal cells, disrupting DNA, RNA and protein synthesis, which prevents fungal growth.
Dosage
Adult Dose:
| Indication | Dose | Schedule |
|---|---|---|
| Seborrheic dermatitis | 5-10 mL (1% shampoo) | Twice weekly for 4 weeks, minimum 3 days between applications |
| Skin fungal infections | Cream | Apply twice daily |
| Fungal nail infection (Onychomycosis) | Topical nail solution | Once daily (at bedtime) for up to 48 weeks |
Pediatric Dose (<10 years): Safety & Efficacy not established.
Administration
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
Missed dose
If you miss a dose of Ciclopirox Topical, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common Side Effects:
- Application site itching
- Burning or stinging sensation
- Skin redness
Precautions & warnings
- For external use only.
- Apply in the dose and duration as advised by your doctor.
- Cover the affected and surrounding skin areas and rub in gently.
- Do not apply more often or use longer than directed (may increase risk of side effects).
- Avoid getting it in your eyes, ears, nose or mouth. If this happens, rinse with water immediately.
- Avoid use of nail varnishes and artificial nails during treatment.
- Do not share your nail-filer to prevent spread of infection.
Contraindications
- Hypersensitivity
- Occlusive wrappings/dressings
Drug interactions
No known drug interactions.
Food interactions
No food interactions found or established.
Use in pregnancy
[SAFE IF PRESCRIBED] Ciclopirox Topical is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Use in lactation
[SAFE IF PRESCRIBED] Ciclopirox Topical is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Pediatric use
Safety and efficacy in children under 10 years have not been established.
Geriatric use
Limited information is available regarding dose adjustment for elderly patients.
Renal / hepatic impairment
Limited information is available regarding use in kidney or liver problems.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Store in a cool and dry place, away from light and out of reach of children.
Chemical structure
Ciclopirox