Cinchocaine Hydrochloride 1%

Cinchocaine Hydrochloride 1% is a local anaesthetic used for surface anaesthesia of the skin. It prevents or diminishes nerve impulse conduction near to the site of administration. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions. This medicine is applied topically as cream or ointment and should be used as directed.

• Surface anaesthesia of the skin

Cinchocaine prevents or diminishes nerve impulse conduction near to the site of administration. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions. It blocks sodium channels, preventing the initiation and conduction of action potentials.

Cinchocaine stabilizes the nerve cell membrane by blocking sodium channels and prevents or diminishes nerve impulse conduction.

Adult Dose (Topical/Cutaneous): Up to 1% in cream and ointment. Use as directed.

This medicine is for external (topical) use only. Apply a small amount of cream or ointment to the affected area. Avoid contact with eyes, mouth, or mucous membranes.

If you miss a dose of Cinchocaine Hydrochloride 1%, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose. Do not double the dose.

Common Side Effects:

• Restlessness
• Excitement, nervousness
• Paraesthesias
• Dizziness
• Tinnitus
• Blurred vision
• Nausea, vomiting
• Muscle twitching, tremors
• Convulsions
• Hypotension
• Bradycardia
• Arrhythmias
• Cardiac arrest

• Elderly, debilitated patients, children, epilepsy, impaired cardiac conduction or respiratory function, shock, hepatic impairment, myasthenia gravis require caution.
• Do not rub or touch the eye while anaesthesia persists.
• Avoid application for prolonged periods and to extensive areas.
• Caution during pregnancy and lactation.

• Complete heart block
• Pyogenic infection at or near the skin
• Application to inflamed or infected tissues or to damaged skin mucosa
• Instillation into the middle ear

No significant drug interactions are known.

No food interactions have been found or established.

Limited information is available regarding use during pregnancy. Avoid application for prolonged periods and to extensive areas. Consult your doctor.

Limited information is available regarding use during breastfeeding. Consult your doctor before use.

Limited information is available regarding use in children. Use with caution.

Use with caution in elderly patients.

For topical use, no dose adjustment is required in renal or hepatic impairment.

Overdose symptoms may include convulsions, respiratory depression, bradycardia, and cardiovascular collapse. Seek immediate medical attention if overdose is suspected.

Store in a cool and dry place, protected from light. Keep out of reach of children.

Cinchocaine Hydrochloride