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Dextrose + Sodium Chloride

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At a glance

Dextrose + Sodium Chloride is an intravenous fluid preparation used for short-term fluid replacement after trauma and electrolyte replenishment.

Description

Dextrose + Sodium Chloride is a sterile solution. Each 100 ml contains Dextrose Monohydrate (5.0 gm) and Sodium Chloride (0.9 gm). It is used for maintenance and replacement of fluid, electrolyte and carbohydrate in patients who are unable to take fluid and nutrients by mouth (e.g., persistent vomiting, during and after surgery, shock or accidents).

Indications
  • Combined water and sodium depletion
  • Maintenance and replacement of fluid, electrolyte and carbohydrate
  • Short-term fluid replacement after trauma
Therapeutic class

Intravenous fluid preparations, Parenteral nutritional preparations

Pharmacological class

Intravenous Fluid Preparation

Pharmacology

Dextrose + Sodium Chloride is a sterile solution used for fluid and electrolyte replenishment and caloric supply. Each 100 ml contains Dextrose 5 gm and Sodium Chloride 0.9 gm, which is isotonic to body fluid.

Mechanism of action

Dextrose + Sodium Chloride provides water, electrolytes, and glucose to the body to replenish fluid deficits.

Dosage

Dosage depends on the clinical condition, age and body surface area of the patient. As directed by a physician.

Administration

Administered intravenously by healthcare professionals. Check infusion set and solution prior to use.

Missed dose

This solution is administered by healthcare professionals. You cannot miss a dose yourself.

Side effects

Common: Febrile response, infection at injection site, venous thrombosis/phlebitis, extravasation, hypervolemia.
Serious: Severe burning, pain, swelling around IV needle; warmth, redness, oozing, bleeding; fever, ongoing cough.

Precautions & warnings

Caution in congestive heart failure, peripheral/pulmonary edema, impaired renal function, pre-eclampsia. Monitor serum glucose in diabetic patients (insulin may be needed). Do not use if solution is cloudy, contains particles, or expired.

Contraindications

Known allergy to corn or corn products (solutions containing dextrose).

Drug interactions

No known drug interactions.

Food interactions

It is not known whether it is safe to consume alcohol with Dextrose + Sodium Chloride. Please consult your doctor.

Use in pregnancy

Pregnancy Category C. Dextrose + Sodium Chloride may be unsafe during pregnancy. Consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Use in lactation

It is not known whether dextrose 5% in water passes into breast milk or if it could harm a nursing baby. Inform your doctor.

Pediatric use

Dosage depends on age, weight and clinical condition of the patient.

Geriatric use

No specific dosage adjustment is necessary for elderly patients.

Renal / hepatic impairment

Renal impairment: Probably unsafe; avoid use. Caution in renal impairment.
Hepatic impairment: Probably safe; dose adjustment may not be needed.

Overdose effects

Treatment of overdose is symptomatic.

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

Chemical structure

Dextrose + Sodium Chloride

Common questions

What is Dextrose + Sodium Chloride used for?
It is used for water and sodium depletion and short-term fluid replacement after trauma.
How is it administered?
It is given as an intravenous infusion by healthcare professionals.
What are the common side effects?
Injection site reactions (fever, infection, phlebitis, hypervolemia).
Who should not use it?
Patients with allergy to corn or corn products.
Can it be used during pregnancy?
Pregnancy Category C, consult your doctor.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.