Ferrous Gluconate

Ferrous gluconate is used in the prevention and treatment of iron-deficiency anaemia. It replaces iron found in haemoglobin, myoglobin and enzymes. It also allows transportation of oxygen via haemoglobin.

Iron is an essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis.

• Iron Deficiency Anemia: Used for treatment and prevention of iron deficiency anemia.

Oral Iron preparations

Iron Replacement

Ferrous gluconate is used in the prevention and treatment of iron-deficiency anaemia. It replaces iron found in haemoglobin, myoglobin and enzymes. It also allows transportation of oxygen via haemoglobin.

Ferrous gluconate replaces iron found in hemoglobin, myoglobin and enzymes and allows transportation of oxygen via hemoglobin.

Adult Dose (Oral):

• Treatment: 60 mg bid up to 60 mg 4 times daily (expressed in terms of elemental iron).
• Prevention: 60 mg daily.

Child Dose (Oral):

• Severe Treatment: 4-6 mg/kg/day in 3 divided doses.
• Mild to Moderate Treatment: 3 mg/kg/day in 1-2 divided doses.
• Prevention: 1-2 mg/kg/day.

For maximum absorption take on empty stomach, but may take with or after meals to minimize GI discomfort.

If you miss a dose of Ferrous Gluconate, take it as soon as possible; however, if it is almost time for your next dose, skip the missed dose.

Common Side Effects:

• Stomach cramping
• Constipation
• Nausea
• Vomiting
• Dark stools
• Heartburn
• Diarrhea
• Teeth staining
• Urine discoloration

Precautions:

• Avoid in patients with peptic ulcer, enteritis, ulcerative colitis and those who receive frequent blood transfusions.
• Not to be used in premature infants until vitamin E stores are replenished.
• Avoid prolonged treatment (>6 months) except in patients with continuous menorrhagia or bleeding.

Contraindications:

• Hemochromatosis
• Hemolytic anemia

Drug Interactions:

• Antacids/H2 antagonists: May reduce absorption of iron.
• Chloramphenicol: May delay response to iron.
• Levodopa, Methyldopa, Penicillamine: May reduce absorption.
• Quinolones or Tetracyclines: May reduce absorption.
• Vitamin C: May increase iron absorption.

Food Interactions: It is not known whether it is safe to consume alcohol with Ferrous Gluconate; consult your doctor.

Use in Pregnancy: Category A; pregnant women typically require increased iron ingestion to meet dietary requirements.

Use in Lactation: Distributed in breast milk; considered safe for breastfeeding; breast milk generally provides enough iron to meet infant nutritional requirement.

Pediatric Use: Child dosage provided above; caution in premature infants.

Geriatric Use: Use with caution in elderly patients.

Renal Impairment: Use with caution in patients with kidney disease.

Hepatic Impairment: Use with caution in patients with liver disease.

Overdose: Iron overdosage is dangerous, especially in children; gastric lavage and desferrioxamine should be administered.

Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.

Ferrous Gluconate