Glucosamine

Introduction: Glucosamine is a medicine used in the treatment of osteoarthritis. It helps in the formation of cartilage and keep the joints lubricated for better movement and flexibility. This way it relieves the pain and swelling in the joints.

How it works: Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage. It is a naturally occurring compound necessary for the body's production of joint lubricants and shock absorbers.

Important Information: Take with food. Take it regularly and do not stop until your doctor tells you. Along with the medicine, exercise regularly.

• Osteoarthritis - of knee, hip, spine, hand and other locations
• Dietary supplement

Stimulation of Cartilage formation

Glucosamine

Glucosamine is a naturally occurring compound necessary for the body's production of joint lubricants and shock absorbers. Glucosamine hydrochloride is a prodrug for glucosamine that is well absorbed after oral administration and diffuses into several tissues, including bones and articular cartilages. Data supports Glucosamine as the first anti-osteoarthritic drug that treats both signs and symptoms of osteoarthritis and modifies disease progression.

Glucosamine helps in cartilage formation, stimulates proteoglycan production and improves joint movement.

Adult Dose:

• 500 mg tablet: 3-4 times daily
• Maximum Dosage: 1500 mg/day
• A single dose of 1500 mg daily may also be effective

Obese individuals: May need higher doses based on body weight

* Use as directed by the registered physician

Oral tablet. Take with food. Swallow whole, do not chew or crush.

If you miss a dose, skip it and continue with your normal schedule. Do not double the dose.

Common Side Effects:

• Nausea
• Upset stomach
• Heartburn
• Mild and reversible intestinal flatulence

Precautions:

• Avoid if allergic to shellfish.
• Diabetics are advised to monitor blood glucose levels regularly when taking Glucosamine.
• Use with caution and medical advice during pregnancy and lactation.
• Do not continue glucosamine if you are having surgery.

Contraindications:

• Allergy to shellfish
• Proven hypersensitivity to Glucosamine

Drug Interactions:

• May reduce effect of antidiabetic agents, doxorubicin, etoposide
• May enhance anticoagulant activity of warfarin

Food Interactions:

• Caution is advised when consuming alcohol. Please consult your doctor.

Use in Pregnancy: Information regarding the use of Glucosamine during pregnancy is not available. Please consult your doctor.

Use in Lactation: Probably safe during breastfeeding. Limited data suggests the drug does not represent significant risk to the baby.

Pediatric Use: Safety and efficacy in children have not been established.

Geriatric Use: No specific dosage adjustment is necessary for elderly patients.

Renal Impairment: Limited information available. Please consult your doctor.

Hepatic Impairment: Limited information available. Please consult your doctor.

Overdose: Safety studies with Glucosamine show no demonstrable toxicity. Rarely occurring side effects are almost like placebo.

Storage: Store in a cool and dry place.

Glucosamine Tablet