Generic
Glucose-1-phosphate
1 brands available in the market
At a glance
Glucose-1-phosphate is a phosphorus supplement used to treat phosphate deficiency in parenteral nutrition.
Description
Introduction: Glucose-1-phosphate is a parenteral nutrition supplement used to treat phosphate deficiency. It delivers nutrients directly into the bloodstream, essential for cellular metabolism, energy production and bone health.
How it works: Phosphate is efficiently absorbed and utilized by the body for energy production via ATP, bone mineralization, cellular membrane function and DNA synthesis. Glucose serves as a primary source of quick energy.
Important Information: Regular monitoring of phosphate levels is necessary to avoid complications from hyperphosphatemia.
Indications
- Phosphate deficiency in parenteral nutrition
Therapeutic class
Parenteral nutritional preparations
Pharmacological class
Phosphorus Supplement
Pharmacology
Phosphate is efficiently absorbed and utilized by the body for energy production via ATP, bone mineralization, cellular membrane function and DNA synthesis. Glucose serves as a primary source of quick energy. Amino acids support the synthesis of proteins for tissue repair, muscle growth, and immune function. Lipids provide essential fatty acids that are used in membrane synthesis and hormone production. Electrolytes help maintain fluid balance, nerve function, and muscle function.
Mechanism of action
Glucose-1-phosphate provides phosphate to the body which is essential for energy production, cellular membrane function and bone health.
Dosage
Adult Dose:
- Dose is individualized based on patient's clinical condition and phosphate requirements
- Administered by intravenous infusion
Administration
Intravenous (IV) infusion. Administered by healthcare professional.
Missed dose
If you miss a dose, consult your doctor.
Side effects
Common Side Effects:
- Hyperphosphatemia - elevated phosphorus levels can lead to calcium-phosphorus precipitation
- Calcification of soft tissues
Precautions & warnings
Precautions:
- Regular monitoring of serum phosphorus is necessary
- To avoid complications from hyperphosphatemia
Contraindications
Contraindications:
- Hypersensitivity to any component of the product (phosphorus, amino acids, glucose, or lipids)
Drug interactions
Drug Interactions: No significant interactions known.
Food interactions
Food Interactions: No interaction found/established.
Use in pregnancy
Use in Pregnancy: Use during pregnancy only if necessary and under the supervision of a healthcare professional.
Pregnancy Category: NA — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Limited data on use during lactation. Consult your doctor.
Pediatric use
Pediatric Use: Use as per doctor's advice for children.
Geriatric use
Geriatric Use: Use as per doctor's advice for elderly patients.
Renal / hepatic impairment
Renal Impairment: Monitor phosphate levels regularly in kidney disease.
Hepatic Impairment: No known restrictions.
Overdose effects
Overdose: Hyperphosphatemia may occur. Monitor phosphorus levels and adjust dose as needed.
Storage conditions
Storage: Store at room temperature (15°C-25°C).
Chemical structure
Glucose-1-phosphate Injection