Generic
Guaifenesin+Dextromethorphan+Menthol
11 brands available in the market
At a glance
Guaifenesin + Dextromethorphan + Menthol is a combination syrup used for chest congestion, cough and sore throat.
Description
Introduction: Guaifenesin + Dextromethorphan + Menthol is a combination syrup used for chest congestion, cough and sore throat.
How it works: Guaifenesin is an expectorant that loosens congestion in the chest and throat, making it easier to cough out. Dextromethorphan Hydrobromide is a cough suppressant that affects signals in the brain that trigger cough reflex. Menthol has local anesthetic and counter irritant qualities and is widely used to relieve throat irritation.
Important Information: Adults and children over 12 years: 2 teaspoonfuls (10 ml) every 6 hours. Maximum 8 teaspoonfuls (40 ml)/day. Do not use for children under 12 years.
Indications
- Chest congestion
- Cough
- Sore throat
Therapeutic class
Combined cough expectorants, Combined cough suppressants
Pharmacological class
Expectorant + Antitussive + Local Anesthetic
Pharmacology
Guaifenesin is an expectorant that loosens congestion in the chest and throat, making it easier to cough out through the mouth. Dextromethorphan Hydrobromide is a cough suppressant that affects signals in the brain that trigger cough reflex. Menthol is an organic compound made synthetically or obtained from corn mint, peppermint or other mint oils. It has local anesthetic and counter irritant qualities and is widely used to relieve throat irritation.
Mechanism of action
Guaifenesin thins mucus, Dextromethorphan suppresses cough reflex and Menthol soothes throat irritation.
Dosage
Adults and children over 12 years:
- 2 teaspoonfuls (10 ml) every 6 hours
- Maximum 8 teaspoonfuls (40 ml)/day
Children under 12 years:
- Do not use
* Use as directed by the registered physician
Administration
Oral syrup. Can be taken with or without food. Take in the dose and duration as advised by your doctor.
Missed dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and follow your regular schedule.
Side effects
Common Side Effects:
- Dizziness
- Drowsiness
- Gastrointestinal disturbance
- Nervousness
- Restlessness
- Anxiety
- Irritability
Precautions & warnings
Precautions:
- Consult doctor before use if you have asthma, chronic lung disease, shortness of breath, persistent cough or taking MAO inhibitor drugs
- Caution while driving or operating machinery
- Avoid alcohol
Contraindications
Contraindications:
- Currently taking MAOI or within 2 weeks of stopping MAOI
Drug interactions
Drug Interactions:
- Possible systemic reactions with acetaminophen, hydrocodone, diphenhydramine, escitalopram, codeine, alprazolam & ondansetron
Food interactions
Food Interactions:
- Caution with alcohol consumption
Use in pregnancy
Use in Pregnancy: Pregnancy Category C. Use only when benefit outweighs risk.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Unknown if dextromethorphan and guaifenesin are excreted in human milk. Use with caution.
Pediatric use
Pediatric Use: Do not use for children under 12 years.
Geriatric use
Geriatric Use: Use as per doctor's advice for elderly patients.
Renal / hepatic impairment
Renal & Hepatic Impairment: No known restrictions. However, consult your doctor.
Overdose effects
Overdose: Guaifenesin overdose is unlikely to produce toxic effect. Dextromethorphan overdose may cause excitement, mental confusion and respiratory depression at very high doses. Menthol in large amounts may cause abdominal pain, diarrhea, nausea, dizziness.
Storage conditions
Storage: Store below 30°C in a cool and dry place, away from light. Keep out of reach of children.
Chemical structure
Guaifenesin + Dextromethorphan + Menthol Syrup