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Generic

Guaifenesin + Levomenthol + Diphenhydramine

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At a glance

Guaifenesin + Levomenthol + Diphenhydramine is a combination syrup used for relief of cough, congestion and sleep disturbances.

Description

Introduction: Guaifenesin + Levomenthol + Diphenhydramine is a combination syrup used for relief of cough, associated congestive symptoms and aiding restful sleep.

How it works: Guaifenesin reduces the viscosity of tenacious sputum and is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.

Important Information: Adults and children over 12 years: 2 teaspoonfuls (10 ml) 4 times a day. Do not take more than 8 teaspoonfuls in 24 hours.

Indications
  • Cough: with associated congestive symptoms
  • Sleep disturbances: aiding restful sleep
Therapeutic class

Combined cough expectorants

Pharmacological class

Expectorant + Antihistamine + Decongestant

Pharmacology

Guaifenesin reduces the viscosity of tenacious sputum and is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.

Mechanism of action

Guaifenesin thins mucus, Levomenthol relieves nasal congestion and Diphenhydramine suppresses cough and induces sleep.

Dosage

Adults and children over 12 years:

  • 2 teaspoonfuls (10 ml) 4 times a day
  • Do not take more than 8 teaspoonfuls in 24 hours

Children & Adolescents:

  • Efficacy and safety not established

* Use as directed by the registered physician

Administration

Oral syrup. Can be taken with or without food. Take in the dose and duration as advised by your doctor.

Missed dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and follow your regular schedule.

Side effects

Common Side Effects:

  • Drowsiness
  • Dizziness
  • Nausea
  • Vomiting
  • Dry mouth
  • Gastro-intestinal disturbance
  • Difficulty in urination
  • Blurred vision
Precautions & warnings

Precautions:

  • May cause drowsiness - do not drive or operate machinery
  • Do not take with narrow-angle glaucoma or symptomatic prostatic hypertrophy
  • Do not use for persistent or chronic cough such as asthma or cough with excessive secretions
  • Do not use in patients who have received MAOIs within last two weeks
Contraindications

Contraindications:

  • Hypersensitivity to the product or any of its components
  • Patients who have received MAOIs within last two weeks
Drug interactions

Drug Interactions:

  • May potentiate effects of alcohol and other CNS depressants
  • Effects of anticholinergics (psychotropic drugs, atropine) may be potentiated
Food interactions

Food Interactions:

  • Alcohol may increase drowsiness and CNS depression
Use in pregnancy

Use in Pregnancy: Use with caution during pregnancy. Not associated with adverse effects in human fetus or suckling infant.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Use in lactation

Use in Lactation: Use with caution during breastfeeding.

Pediatric use

Pediatric Use: Efficacy and safety in pediatric patients and adolescents have not been established.

Geriatric use

Geriatric Use: Use as per doctor's advice for elderly patients.

Renal / hepatic impairment

Renal & Hepatic Impairment: No known restrictions. However, consult your doctor.

Overdose effects

Overdose: Guaifenesin may cause renal calculi when taken in excess. Treatment should be symptomatic and supportive.

Storage conditions

Storage: Store at a temperature not exceeding 30°C in a dry place. Protect from light and moisture. Keep out of reach of children.

Chemical structure

Guaifenesin + Levomenthol + Diphenhydramine Syrup

Common questions

Q1: What is this syrup used for?
It is used for relief of cough, congestion and sleep disturbances.
Q2: What are the side effects?
Drowsiness, dizziness, nausea and dry mouth.
Q3: What precautions should be taken?
Do not drive, avoid alcohol and do not use if you have glaucoma or prostatic problems.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.