Generic
Guaifenesin + Levomenthol + Diphenhydramine
20 brands available in the market
At a glance
Guaifenesin + Levomenthol + Diphenhydramine is a combination syrup used for relief of cough, congestion and sleep disturbances.
Description
Introduction: Guaifenesin + Levomenthol + Diphenhydramine is a combination syrup used for relief of cough, associated congestive symptoms and aiding restful sleep.
How it works: Guaifenesin reduces the viscosity of tenacious sputum and is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.
Important Information: Adults and children over 12 years: 2 teaspoonfuls (10 ml) 4 times a day. Do not take more than 8 teaspoonfuls in 24 hours.
Indications
- Cough: with associated congestive symptoms
- Sleep disturbances: aiding restful sleep
Therapeutic class
Combined cough expectorants
Pharmacological class
Expectorant + Antihistamine + Decongestant
Pharmacology
Guaifenesin reduces the viscosity of tenacious sputum and is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.
Mechanism of action
Guaifenesin thins mucus, Levomenthol relieves nasal congestion and Diphenhydramine suppresses cough and induces sleep.
Dosage
Adults and children over 12 years:
- 2 teaspoonfuls (10 ml) 4 times a day
- Do not take more than 8 teaspoonfuls in 24 hours
Children & Adolescents:
- Efficacy and safety not established
* Use as directed by the registered physician
Administration
Oral syrup. Can be taken with or without food. Take in the dose and duration as advised by your doctor.
Missed dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and follow your regular schedule.
Side effects
Common Side Effects:
- Drowsiness
- Dizziness
- Nausea
- Vomiting
- Dry mouth
- Gastro-intestinal disturbance
- Difficulty in urination
- Blurred vision
Precautions & warnings
Precautions:
- May cause drowsiness - do not drive or operate machinery
- Do not take with narrow-angle glaucoma or symptomatic prostatic hypertrophy
- Do not use for persistent or chronic cough such as asthma or cough with excessive secretions
- Do not use in patients who have received MAOIs within last two weeks
Contraindications
Contraindications:
- Hypersensitivity to the product or any of its components
- Patients who have received MAOIs within last two weeks
Drug interactions
Drug Interactions:
- May potentiate effects of alcohol and other CNS depressants
- Effects of anticholinergics (psychotropic drugs, atropine) may be potentiated
Food interactions
Food Interactions:
- Alcohol may increase drowsiness and CNS depression
Use in pregnancy
Use in Pregnancy: Use with caution during pregnancy. Not associated with adverse effects in human fetus or suckling infant.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Use with caution during breastfeeding.
Pediatric use
Pediatric Use: Efficacy and safety in pediatric patients and adolescents have not been established.
Geriatric use
Geriatric Use: Use as per doctor's advice for elderly patients.
Renal / hepatic impairment
Renal & Hepatic Impairment: No known restrictions. However, consult your doctor.
Overdose effects
Overdose: Guaifenesin may cause renal calculi when taken in excess. Treatment should be symptomatic and supportive.
Storage conditions
Storage: Store at a temperature not exceeding 30°C in a dry place. Protect from light and moisture. Keep out of reach of children.
Chemical structure
Guaifenesin + Levomenthol + Diphenhydramine Syrup