Generic
Hydrocortisone Acetate + Benzyl Benzoate + Bismuth Subgallate + Bismuth Oxide + Balsam Peru + Zinc Oxide
1 brands available in the market
At a glance
Hydrocortisone Acetate + Benzyl Benzoate + Bismuth Subgallate + Bismuth Oxide + Balsam Peru + Zinc Oxide ointment is used for the comprehensive symptomatic treatment of internal and external hemorrhoids and pruritus ani.
Description
This ointment is used for the comprehensive symptomatic treatment of internal and external hemorrhoids and pruritus ani. It contains Hydrocortisone Acetate (anti-inflammatory), Benzyl Benzoate (mild antiseptic and preservative), Bismuth Subgallate and Bismuth Oxide (protective and mild astringent on mucous membranes), Balsam Peru (protective and mild antiseptic) and Zinc Oxide (protective and astringent).
Indications
- Internal hemorrhoids
- External hemorrhoids
- Pruritus ani (anal itching)
Therapeutic class
Other Topical corticosteroids
Pharmacological class
Topical Corticosteroid + Antiseptic + Astringent
Pharmacology
This ointment provides antiseptic, astringent, emollient and anti-inflammatory actions. Bismuth oxide, zinc oxide, and bismuth subgallate exert a protective action on mucous membranes, are mildly astringent and have antiseptic properties. Balsam Peru has protective properties and mild antiseptic action by virtue of its content of cinnamic and benzoic acids. It is believed to promote the growth of epithelial cells. Hydrocortisone acetate has anti-inflammatory action.
Mechanism of action
Hydrocortisone acetate reduces inflammation; Bismuth and Zinc compounds provide protective barrier; Balsam Peru promotes wound healing and provides antiseptic action.
Dosage
Adult Dose (18+ years):
- Apply sparingly to affected area at night, in the morning and after each evacuation (max 4 applications/day)
- Thoroughly cleanse affected area, dry and apply ointment on gauze dressing
- For internal conditions use the rectal applicator provided
- Use for a maximum period of one week
Pediatric Use: Not recommended for children under 18 years old
Administration
For topical use only; cleanse and dry affected area; apply at night, morning and after each evacuation; use rectal applicator for internal use.
Missed dose
If you miss a dose, apply it as soon as possible; if it is almost time for your next dose, skip the missed dose.
Side effects
Side Effects:
- Prolonged or excessive use may produce systemic corticosteroid effects (max 7 days)
- Sensitivity reactions (rare)
- Transient burning on application (especially if anoderm is not intact)
Precautions & warnings
Precautions:
- Possibility of systemic absorption of topical steroids should be borne in mind
- Prolonged or excessive use may produce systemic corticosteroid effects (not recommended for more than 7 days)
- Discontinue and consult doctor if symptoms do not improve or worsen or if rectal bleeding occurs
Contraindications
Contraindications:
- Tubercular, fungal and most viral lesions (including herpes simplex, vaccinia and varicella)
- History of sensitivity to any constituents
Drug interactions
Concurrent use with other corticosteroid preparations either topically or orally may increase the likelihood of systemic effects.
Food interactions
No food interaction found/established.
Use in pregnancy
Use in Pregnancy: Inadequate evidence of safety in human pregnancy; very small risk of cleft palate, intrauterine growth retardation and neonatal HPA axis suppression; use only when no safer alternative and when disease itself carries risks for mother or child.
Use in lactation
Use in Lactation: No special precautions required for use during lactation.
Pediatric use
Not recommended for children under 18 years.
Geriatric use
No specific precautions for elderly; however caution is advised.
Renal / hepatic impairment
No specific data for renal or hepatic impairment.
Overdose effects
No information on overdose; do not exceed the recommended dose.
Storage conditions
Do not store above 30°C & keep in a dry place; protect from light; do not freeze; keep out of reach of children.
Chemical structure
Hydrocortisone Acetate + Benzyl Benzoate + Bismuth Subgallate + Bismuth Oxide + Balsam Peru + Zinc Oxide Ointment