Generic
Ketoconazole + Zinc Pyrithione + Aleovera
2 brands available in the market
At a glance
Ketoconazole + Zinc Pyrithione + Aleovera shampoo is used for curing various issues of scalp and hair, especially dandruff, seborrheic dermatitis, and pityriasis versicolor.
Description
Ketoconazole + Zinc Pyrithione + Aleovera shampoo contains three active ingredients that help cure various scalp and hair issues. Ketoconazole is an antifungal agent that inhibits ergosterol synthesis in fungal cell membranes to stop Malassezia fungal growth. Zinc Pyrithione is an antifungal and antibacterial agent that works against microorganisms causing dandruff. Aloe vera is a natural ingredient that soothes and moisturizes the scalp. This shampoo is clinically tested and proven safe for all skin types.
Indications
- Dandruff (pityriasis capitis)
- Seborrheic dermatitis
- Pityriasis versicolor
- Fungal infections of the scalp
- Helps soothe scalp irritation and hair loss
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Antifungal + Antibacterial + Moisturizer
Pharmacology
Ketoconazole is an azole antifungal that interacts with 14-α-sterol demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. It inhibits ergosterol synthesis and increases fungal cell membrane permeability. Zinc Pyrithione is an antifungal and antibacterial agent that works against microorganisms causing dandruff. Aloe vera is a natural ingredient that soothes and moisturizes the scalp.
Mechanism of action
Ketoconazole kills fungi by inhibiting ergosterol synthesis in fungal cell membranes; Zinc Pyrithione provides antifungal and antibacterial action; Aloe vera soothes and moisturizes the scalp.
Dosage
Adult Dose (Topical):
- Use twice weekly, or as prescribed by a doctor
- Apply sufficient shampoo to wet hair and scalp to produce enough lather
- Massage for 2 minutes, then rinse with water
Child Dose: No specific data; use as directed by physician
Administration
Apply on wet hair and scalp; use sufficient shampoo to produce enough lather; massage for 2 minutes; rinse with water; use twice weekly or as prescribed by doctor.
Missed dose
If you miss a dose, apply it as soon as possible; if it is almost time for your next application, skip the missed dose and go back to regular schedule.
Side effects
Common Side Effects:
- Mild burning at application site
- Itching
- Dry skin
- Oily or dry hair (rare)
Precautions & warnings
Precautions:
- For external use only
- Avoid contact with eyes; if contact occurs, rinse with water
- Keep out of reach of children
- Discontinue use if skin irritation or allergy occurs
Contraindications
Contraindications:
- Hypersensitivity to any ingredients
Drug interactions
No significant drug interactions known (topical use).
Food interactions
No food interactions applicable (topical use).
Use in pregnancy
Use in Pregnancy: Generally safe due to topical use; however consult your doctor.
Use in lactation
Use in Lactation: Generally safe due to topical use; however consult your doctor.
Pediatric use
Safe for children; use as directed by physician.
Geriatric use
Safe for elderly; no special precautions needed.
Renal / hepatic impairment
No interactions applicable for renal or hepatic impairment (topical use).
Overdose effects
Overdose not applicable (topical use).
Storage conditions
Keep below 30°C temperature, away from light & moisture; keep out of reach of children.
Chemical structure
Ketoconazole + Zinc Pyrithione + Aleovera Shampoo