Methoxsalen

Methoxsalen is a medicine used along with controlled ultraviolet light for effective treatment of certain skin diseases like vitiligo and psoriasis. Methoxsalen is taken after meals in a dose and duration as advised by the doctor. Taking with food helps to increase absorption of the medication as well as decreases nausea. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects of Methoxsalen are nausea, itching, and redness of the skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make dizziness worse. Taking this medicine makes the skin more sensitive to the sun. Use a sunscreen and wear protective clothing when outdoors. Try to avoid exposure of your skin and lips to sunlight for eight hours after treatment. Methoxsalen is a organic compound. It is used along with ultraviolet-A irradiation. It works by decreasing the number of cells the skin makes.

• Vitiligo • Psoriasis

Methoxsalen increases skin reactivity to long-wavelength UV rays. It bonds covalently to DNA inhibiting DNA synthesis and cell division, which can lead to cell injury. This effect is used in photochemotherapy or PUVA and high-intensity long-wavelength UVA irradiation].

Adult Dose: Topical Vitiligo: Adults and children 12 years of age and over Apply to the affected area of the skin 2 hr before UV exposure q3-7 days. The amount and time of UVA light for each treatment is based on skin type and response to treatment. patient may have UVA light treatments 2 to 4 times a week when first start and then less frequently as condition improves. Child Dose: Topical Vitiligo: Children 12 years of age and over Apply to the affected area of the skin 2 hr before UV exposure q3-7 days. <12 years old: safety and efficacy not established

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Methoxsalen is to be taken with food.

Common: • Itching

[CONSULT YOUR DOCTOR] It is not known whether Methoxsalen alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Take this treatment (methoxsalen and UVA) two or three times a week with the treatment spaced at least forty-eight hours apart. Take this medication by mouth with food or milk, usually 2 to 4 hours before your UVA light treatment. Do not sunbathe for 24 hours before taking methoxsalen. Wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or use a sunblock (SP 15 or higher) for the twenty-four (24) hour period following treatment with methoxsalen. Use extra caution for at least 48 hours following each treatment. After each treatment, cover your skin for at least 8 hours by wearing protective clothing. Do not increase the amount of methoxsalen if you are taking or spend extra time in the sunlight or under an ultraviolet lamp. Do not drive or operate machinery as methoxsalen may cause dizziness. Not recommended for use in children younger than 12 years. You will need to have an eye examination before starting methoxsalen and also once a year thereafter.

Hypersensitivity. Aphakia, existing or history of melanoma, invasive squamous cell carcinoma, photosensitivity diseases (e.g. porphyria, acute lupus erythematosus, xeroderma pigmentosum).

Additive effects with drugs known to cause photosensitisation e.g. anthralin, coal tar or derivatives, griseofulvin, phenothiazines, nalidixic acid, sulfonamides., tetracyclines and thiazide diuretics. May increase the levels/effects of aminophylline, fluvoxamine, mexiletine, mirtazapine, ropinirole, theophylline, trifluoperazine, dexmedetomidine and ifosfamide.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Methoxsalen. Please consult your doctor.

[CONSULT YOUR DOCTOR] Methoxsalen is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

[CAUTION] Methoxsalen should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Methoxsalen in patients with kidney disease. Please consult your doctor. [CAUTION] Methoxsalen should be used with caution in patients with liver disease. Dose adjustment of Methoxsalen may be needed. Please consult your doctor.

I get lot of sun exposure Daily, I have Vertiligo I take Melanocyl tablets and take sun exposure daily Dear Sir Greetings from 1mg. Please consult a Dermatologist for this. Lecoderma treatment Currently consuming Trimop forte nd Melanocyl with sun exposure for pigmentation and Minoz 50 since last one year. Though some parts got pigmented but not fully cured Suggest further action You may require NBUVB phototherapy, kindly consult a dermatologist near you. best treatment for vitiligo??? Recently I use tacrolimus,placenta extract ointment and trioxsalen tablet I can understand your problem but you need to understand that vitiligo has a tendency to spread in due course of time, and hence it is always better to consult a dermatologist personally as you are intelligent enough to understand the fact that we cannot prescribe any medication which have a lot of side effects online, as it can harm you. You need proper treatment regimen with few oral medications too. Please visit nearby dermatologist personally for through clinical examination along with laboratory tests How to increase sex mood for a longer time as well I am trying for 2nd kid what medicine can be taken? I m having psoriasis disease also what can be done Take vigomax forte tablet 2 tablet twice, chandraprabha vati 2 tab twice, speman tablet 2 tablet twice, for psoriasis its better to go for Panchkarma specialist vitiligo on lips, my father also vitiligo Difficult to treat, you should visit skin specialist for proper examination and treatment vitiligo 60% all along the body No family histroy of vitiligo Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed. She is having white/pink patches on lip(differing the lip color). Earlier she was having blister (?????)on lip. What is it? It is Post herpetic leucoderma which may progress to frank vitiligo. Are psoralens good for vitiligo Ds psoralens improves the lesions of. Vitiligo as lesions cause psychological discomfort Psoralens not good in vitiligoSend pictures of the affected area