Generic
Niacinamide + Pyridoxine + Riboflavin + Thiamine
1 brands available in the market
At a glance
Niacinamide + Pyridoxine + Riboflavin + Thiamine is a vitamin B-complex combination used for vitamin B deficiency, skin & nervous system problems, intense physical activity, optic neuritis and peripheral neuritis.
Description
Vitamin B plays a role in synthesis and maintenance of coenzyme A, necessary for lipid metabolism, carbohydrate metabolism, tissue respiration and glycogenolysis. Pyridoxine functions in metabolism of carbohydrates, proteins and fats, essential in Hb formation and GABA synthesis. Riboflavin is required for energy utilization from food and essential for normal tissue respiration. Thiamine forms thiamine pyrophosphate, an essential coenzyme in carbohydrate metabolism.
Indications
- Vitamin B deficiency
- Skin & nervous system problems
- Intense physical activity
- Optic neuritis
- Peripheral neuritis
Therapeutic class
Vitamin-B Complex Preparations
Pharmacological class
Water-soluble Vitamin Combination
Pharmacology
Vitamin B plays a role in coenzyme A synthesis and maintenance. Pyridoxine functions in carbohydrate, protein and fat metabolism, essential in Hb formation and GABA synthesis. Riboflavin is required for energy utilization from food. Thiamine is an essential coenzyme in carbohydrate metabolism.
Mechanism of action
Corrects vitamin B deficiency and improves nerve and skin health.
Dosage
Adult Dose (Syrup):
- 10 ml (2 teaspoonful) twice daily
Pediatric Dose (Syrup):
- 1 teaspoonful (5 ml) twice daily
Administration
- Use measuring spoon
- Take at the same time each day
- Best taken with food
Missed dose
If you miss a dose, take it as soon as you remember; skip if it's almost time for next dose; do not double the dose.
Side effects
Side Effects:
- Generally well tolerated
Precautions & warnings
- Take at recommended dosage
Contraindications
- Hypersensitivity to any components
Drug interactions
- Pyridoxine: Isoniazid, penicillamine and oral contraceptives may increase pyridoxine requirement; reduces effects of levodopa, phenobarbitone, altretamine and phenytoin
- Riboflavin: Propantheline bromide may affect rate and extent of absorption
Food interactions
Take with food for better absorption.
Use in pregnancy
Use in Pregnancy: Safe during pregnancy; consult doctor.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Safe during breastfeeding; consult doctor.
Pediatric use
Dose established for children.
Geriatric use
Indicated for adults.
Renal / hepatic impairment
Renal Impairment: Caution in kidney disease; dose adjustment may be needed.
Hepatic Impairment: Caution in liver disease; dose adjustment may be needed.
Overdose effects
Overdose may cause vitamin toxicity; symptomatic treatment.
Storage conditions
Store in a cool and dry place, away from light; keep out of reach of children.
Chemical structure
Niacinamide + Pyridoxine + Riboflavin + Thiamine